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11

Gene may open door for new sickle cell therapies

piggy submitted, created time 1 month 1 day (www.reuters.com)

U.S. researchers have discovered a gene switch that could lead to better treatments for sickle cell disease and thalassemia, two inherited blood disorders that affect millions of people, they said on Thursday.

Learning how to activate this switch might help doctors direct the body to make healthier blood cells -- in this case, replicating conditions found in the womb.
People with these blood disorders either make too little or abnormal forms of hemoglobin, the protein in red blood cells that is vital for carrying oxygen to the body's tissues

11

Blood tests may show inherited diseases in fetuses

sea-maid submitted, created time 1 month 1 week (www.reuters.com)

Doctors may soon be able to diagnose inherited diseases such as cystic fibrosis, thalassaemia and sickle cell anemia in fetuses by simply testing a blood sample taken from the mother.

5

Danger coming with hope: Amgen's Anemia Drugs Ailing

DanyC submitted, created time 10 months 1 week (www.forbes.com)

There is a $10 billion market for drugs to treat the anemia that occurs after kidney dialysis and cancer chemotherapy. Well, a new study said Amgen and Johnson & Johnson's anti-anemia treatments raise the risk of death via blood clots, and worries coming, that these medicines actually harm patients when overused have caused doctors to limit prescriptions.

8

Prediction of adverse outcomes in children with sickle cell anemia: a study of the Dallas Newborn Cohort

davidd submitted, created time 11 months 2 weeks (bloodjournal.hematologylibrary.org)

The Cooperative Study of Sickle Cell Disease reported that dactylitis, severe anemia, and leukocytosis in very young children with sickle cell disease (SCD) increased the risk of later adverse outcomes, including death, stroke, frequent pain, and recurrent acute chest syndrome. They established a prediction model of adverse outcomes in children with sickle cell anemia. The model will helps doctors choose better treatment for newborn with Sickle Cell Disease to reduce fatal rate.

8

Reprogrammed Skin Cells Strut Their Stuff

Eric wu submitted, created time 1 year 1 month (sciencenow.sciencemag.org)

I am so excited when I read this good news.No doubt,It has taken a hopeful light for our human being to conquer sickle cell anemia.

It has been reported that common skin cells transfered to stem cells by adding four special genes two weeks ago.It also has a debate in China. A Chinese scientist whose name is not specific to me wrote a article in China GuangMing Daily to declare that the new breakthrough on stem cell research has referred to his achievement more or less. But another Chinese scientist who is famous for revealing false science made a face for his action

7

Good News:Transplants Without Tears

Eric wu submitted, created time 1 year 1 month (sciencenow.sciencemag.org)

A new treatment might allow patients to avoid some of the grueling side effects of bone marrow transplants. Researchers reported in the 23 November issue of Science that they can use a specific type of antibody to clear away old marrow stem cells in mice, allowing fresh ones to take their place. The discovery could allow patients to receive bone marrow without undergoing chemotherapy and other toxic procedures.

6

Celiac disease cured after leukemia treatment

annatto submitted, created time 1 year 2 months (www.reutershealth.com)

The findings of a case report of a child with leukemia indicate that celiac disease, a common digestive problem in which the body cannot breakdown and absorb a protein found in wheat, may resolve following stem cell transplantation.

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