Articles with the keyword:
11

FDA: Epilepsy drug may be risky for Asians

piggy submitted, created time 1 month 1 week (www.fda.gov)

FDA is investigating new preliminary data regarding a potential increased risk of serious skin reactions including Stevens Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) from phenytoin therapy in Asian patients positive for a particular human leukocyte antigen (HLA) allele, HLA-B*1502. This allele occurs almost exclusively in patients with ancestry across broad areas of Asia, including Han Chinese, Filipinos, Malaysians, South Asian Indians, and Thais

11

Light Triggers New Code for Brain Cells

piggy submitted, created time 1 month 3 weeks (www.sciencedaily.com)

Brain cells can adopt a new chemical code in response to cues from the outside world, scientists working with tadpoles at the University of California, San Diego report in the journal Nature.

The discovery opens the possibility that brain chemistry could be selectively altered by stimulating specific circuits to remedy low levels of neural chemicals that underlie some human ailments.

Dark tadpoles don pale camouflage when exposed to bright light

12

Tumorigenesis: Keeping a watchful eye

sea-maid submitted, created time 2 months 2 weeks (www.nature.com)

Disruptions in the delicate balance between keratinocyte proliferation and differentiation can contribute towards the development of squamous cell carcinoma (SCC) of the skin — a common human malignancy. It has been proposed that innate surveillants, molecules that promote terminal keratinocyte differentiation, exist in the skin to prevent carcinogenesis, but the conclusive identification of such proteins has not yet been achieved

7

UV light fear over

sea-maid submitted, created time 2 months 4 weeks (news.bbc.co.uk)

You know those fluorescent bulbs that save so much energy (and money) and have been promoted by everyone from environmental groups to Wal-Mart? Well they emit UV light.

So should you chuck them in the trash (Oh, this is a BBC article. I'd better say "bin.")? Nope! According to the British Health Protection Agency, being within one foot of an exposed coil is no more dangerous than being outside on a sunny day. Bulbs that are covered up by casings are even less troublesome

8

Cosmetics companies mince words

Darkfrog submitted, created time 3 months 6 days (www.nytimes.com)

The next time you pick up a bottle of shampoo or moisturizer, take a look at the label. Does it claim to contain stem cells or growth hormone? For people who hang out on this website, the thought is probably, "Wait. Laboratories have a hard enough time growing their own stem cells. Who the #@%& is $#%!headed enough to put them in a 'rejuvenating night cream'?!"

It's hype. Of course it's hype

10

Moisturizers Up Skin Cancer

kavin submitted, created time 4 months 3 weeks (www.medscape.com)

Four commonly used moisturizers promoted skin cancers in mouse studies.

Mice are not men. But the unexpected finding suggests that these — and perhaps other products — may not be as safe as they're thought to be.

The moisturizers tested in the study were Dermabase, Dermovan (a wholesale-only product discontinued in 2006), Eucerin Original Moisturizing Cream, and Vanicream.

In a mouse model of sun-related skin cancer, frequent application of each product resulted in more skin tumors and faster tumor growth, says study leader Allan H

8

Breaking out new ideas on molting

kavin submitted, created time 6 months 3 weeks (www.jcb.org)

Alison Frand believes that understanding the molting process of the nematode worm, C. elegans, might provide new insights into diseases affecting humans. Some of the potential medical benefits lie in the similarities between the worms' exoskeleton and our own skin and connective tissues, while other benefits might lie in the unique aspects of worm molting. Alison Frand is using RNAi, GFP-PEST, and other state-of-the-art tools to study molting in worms.

11

Stem cell treatment leaves boy with recessive epidermolysis bullosa improving daily

Darkfrog submitted, created time 6 months 4 weeks (www.latimes.com)

Two-year-old Nate Liao is eating solid food, playing with his sibs and generally running around and getting into things. The reason? His body has started producing collagen VII, the material that anchor's a person's skin to the rest of his body. Before he was treated, the least contact could cause bruising and blisters. Eating anything non-liquid could tear the lining of his esophagus.

Some of Nate's doctors are suggesting that epidermolysis bullosa be taken "off the incurable list." Little Nate was given a mixture of bone marrow and cord blood stem cells

9

Mice Sniff Out Oxygen With Their Skin

lily0558 submitted, created time 8 months 2 weeks (www.cell.com)

In this paper, researchers have found that a mouse's skin can sense oxygen levels in the air and that it helps regulate the number of oxygen-carrying red blood cells in the body. It is potential that human skin may behave the same way, which could open the door for new ways to boost blood cell levels for athletes seeking to gain an edge or patients with anemia. But they don't yet know how the skin senses the gas.It maybe because of mouse skin containing the same oxygen-sensitive potassium channels as the lung. Humans also carry the HIF-1α gene

8

Atopic Dermatitis

Vincent submitted, created time 9 months 4 days (content.nejm.org)

Atopic dermatitis, or eczema, is a common skin disease that is often associated with other atopic disorders, such as allergic rhinitis and asthma 1. The clinical manifestations of atopic dermatitis vary with age; three stages can often be identified. In infancy, the first eczematous lesions usually emerge on the cheeks and the scalp. Scratching, which frequently starts a few weeks later, causes crusted erosions. During childhood, lesions involve flexures, the nape, and the dorsal aspects of the limbs. In adolescence and adulthood, lichenified plaques affect the flexures, head, and neck

7

UCLA joins skin-to-stem-cell club

Sue Wu submitted, created time 10 months 3 weeks (www.efluxmedia.com)

US scientists said they have successfully reprogrammed human skin cells to behave exactly as embryonic stem cells. The research was published in the Feb. 11 edition of the journal Proceedings of the National Academy of the Sciences. This is the third such confirmation that the technique is feasible

5

A Clockwork Skin Cell

sumsung submitted, created time 11 months 1 week (sciencenow.sciencemag.org)

Are you a lark who springs from bed at dawn, or a night owl happy staying up late? Your skin knows, according to a new study. By testing skin samples from people with sleep problems, researchers have found the first ties between people's behavior and the biological clocks they carry in their cells. The discovery could lead to cheaper and more practical ways to diagnose and treat sleep disorders and other ailments.

8

There's No Hiding This Camouflage

sumsung submitted, created time 11 months 1 week (sciencenow.sciencemag.org)

Everyone knows what makes the chameleon so special: its rapid color-changing camouflage. But the bug-eyed lizard's reputation as a master of disguise is being challenged by new research published today in PLoS Biology. Its flexible pigmentation may actually be a sexy, albeit dangerous, way to stick out.

5

When Surgery Succeeds, But Healing Fails

Eric wu submitted, created time 1 year 1 month (www.time.com)

A surgeon uses a scalpel to incise the skin, beginning an exploratory celiotomy....... But when a wound doesn't heal, what then? Professor of Orthopedic Surgery adds another d to "FRIEND."

7

The elderberry way to perfect skin

bianjie submitted, created time 1 year 6 months (www.eurekalert.org)

Forget expensive moisturisers and cosmetic surgery, a compound found in the humble elderberry could give a natural boost to skin. In the first study of its kind, the University of East Anglia and the Institute of Food Research will explore whether the skin's condition is improved by a compound which gives berries their vibrant color.

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