Articles with the keyword: 
Darkfrog submitted, created time 1 week 3 days (www.nature.com)
Researchers from Harvard have found that using adenoviruses to reprogram cells can avoid some of the risk of making induced pluripotent stem cells. Instead of integrating into the host cell's DNA, the adenoviruses express the genes themselves.
So far, the experiments have only been successful in mouse tail and liver cells, which are much less hard to work with than primate cells and tissues. In addition, the overall success rate is much lower than that of integrating virus methods, reprograming cells only 0.0001% to 0.001% of the time 
Retinal transplants bear threefold fruit
Darkfrog submitted, created time 3 weeks 6 days (www.nature.com)
A formerly clinically blind woman's vision improved from 20/800 to 20/160--from one-fortieth of ordinary vision to one-eighth--after receiving donated retina. Six months after the operation, the started noticing the pendulum in her grandfather clock. For years, she found that she could read large-print books and emails and returned to her hobbies, knitting and sewing. Now, six years after her operation, her vision is fading, but it is still better than it was before the operation
Republican presidential platform would ban all human embryonic research
Darkfrog submitted, created time 1 month 4 days (www.nature.com)
The Republican presidential platform proposes banning all human embryo research throughout the United States. Although John McCain himself has voted to loosen federal restrictions on stem cell funding, the party that supports him appears to be taking a more conservative line.
But for the grammar enthusiasts among us, the change in the platform was effected with one word. They canged "and" to "or," so that they call for a ban on the "the creation of or experimentation on human embryos for research purposes
sea-maid submitted, created time 1 month 1 week (www.nature.com)
Observers could be forgiven for thinking they had spotted a phoenix rising from the ashes of Advanced Cell Technology (ACT) earlier this week. The Los Angeles, California-based company, which is devoted to turning human embryonic stem cells into therapies, had been reported on the verge of extinction last month after it told the U.S. Securities and Exchange Commission that it would run out of money on 31 July
New mouse stem cell is just like ours
sea-maid submitted, created time 1 month 2 weeks (www.newscientist.com)
The discovery of a mouse embryonic stem cell that is a near-perfect match to human cells may speed research in new treatments for injury and disease.
Taking cells from mouse embryos at later stages--epiblasts instead of blastomeres--seems to prevent them from developing the traits that make them so very different from human cell lines. This has many scientists pondering the evolutionary differences between humans and mice, but the real kicker seems to be that primate stem cell lines are much more difficult to culture than lines made from other species
Stem cells from menstrual blood save limbs
sea-maid submitted, created time 1 month 2 weeks (www.newscientist.com)
Stem cells derived from human menstrual blood have, in mice, prevented limbs with restricted blood flow from withering. Trials in humans facing amputations are expected to start next year.
First red blood cells grown in the lab
sea-maid submitted, created time 1 month 2 weeks (www.newscientist.com)
Blood donations may one day be a thing of the past thanks to the creation of the first functional red blood cells grown in the lab. The cells were grown from human embryonic stem cells (ESCs).
When the past catches up with the present
sea-maid submitted, created time 1 month 2 weeks (www.nature.com)
Oversight committees face tough decisions after an analysis questions whether certain cell lines meet standards of informed consent. If not, then the number of stem cell lines that U.S. scientists may study with federal funding may drop from twenty-one to sixteen.
Induced stem cell lines may soon be available from Harvard
Darkfrog submitted, created time 1 month 4 weeks (sciencenow.sciencemag.org)
A few weeks ago, we talked about how researchers had been able to take a cell from an ALS patient and develop a working, research-quality pluripotent cell line. Well the next step has been taken.
I've been saying that induced pluripotent stem cells might become the preferred research model (over embryonic stem cells), but only if they became easier to obtain than embryonic stem cells. It looks as though that might happen soon. The Harvard Stem Cell Institute is dedicating an iPS core lab
Induced stem cells become research model for ALS
Darkfrog submitted, created time 2 months 5 days (sciencenow.sciencemag.org)
Induced stem cells are coming into their own as a research model. Scientists at Harvard and Columbia have created a culture of motor cells from the skin of a patient known to be afflicted with amyotropic lateral sclerosis, also known as Lou Gherig's disease.
The patient has a rare form of ALS that is known to be caused by an inherited mutation. This represents only 2% of ALS patients. This may be significant because critics claim that partial replicants of the patient's nerve cells will be of little use as research models
Consent issues restrict stem-cell use and research
sea-maid submitted, created time 2 months 1 week (www.nature.com)
Some researchers in Stanford University are told that around one-quarter of the human embryonic stem-cell lines eligible for U.S. government funding are now off-limits because of ethical concerns. The university is concerned that some of the women who donated the embyros that were used to generate the line might not have been fully informed of how they would be used.
The consent forms that the women signed were retrieved and it was found that none of them met Standford's guidelines exactly and some of them were way off the mark
Embryonic stem cells answer questions about breast cancer
sea-maid submitted, created time 2 months 1 week (www.nature.com)
Mutations in the BRCA1 and BRCA2 genes dramatically increase a woman's risk of breast cancer, and some women consider genetic screening in the hopes of earlier detection and treatment. Commercial tests can detect common variants associated with risk, but many mutations are unclassified
sea-maid submitted, created time 2 months 1 week (www.nature.com)
Developing a way to reliably produce hematopoietic stem cells is a bloody tough problem. Unlike most tissues, cells of the hematopoietic system emerge from several embryonic sites and then circulate through the body. This mobility has perplexed researchers, who hope that mimicking the in vivo environment will help them culture these stem cells. Now, two British research teams report in Cell Stem Cell their complementary techniques for isolating these cells. These methods could form the lifeblood of creating easier alternatives to bone marrow transplantation.
Heart Blood Vessels Grown in the Lab
sea-maid submitted, created time 2 months 2 weeks (www.washingtonpost.com)
Researchers say they have grown in mice the kind of functioning heart blood vessels that cardiac surgeons create with bypass operations.
Can you turn teeth into sperm?
sea-maid submitted, created time 2 months 2 weeks (www.newscientist.com)
COULD sacrificing a tooth enable some infertile men to father children? That's the goal of researchers in Brazil, who suggest that stem cells from human teeth can be coaxed into becoming sperm by being injected into the testes of mice.
Irina Kerkis of the Butantan Institute in São Paulo and her colleagues injected stem cells from the dental pulp of human teeth into the testes of live mice. The cells seemed to migrate to the tubules where sperm usually mature and differentiate into cells resembling human sperm
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