Articles with the keyword: 
Darkfrog submitted, created time 1 week 3 days (www.nature.com)
Researchers from Harvard have found that using adenoviruses to reprogram cells can avoid some of the risk of making induced pluripotent stem cells. Instead of integrating into the host cell's DNA, the adenoviruses express the genes themselves.
So far, the experiments have only been successful in mouse tail and liver cells, which are much less hard to work with than primate cells and tissues. In addition, the overall success rate is much lower than that of integrating virus methods, reprograming cells only 0.0001% to 0.001% of the time 
Politics: U.S. presidential candidates outline their positions on science issues
Darkfrog submitted, created time 2 weeks 6 days (www.nytimes.com)
Senator Obama focused more on the government's role in supporting basic research while Senator McCain favored tax breaks for private businesses, but both candidates claim to support education, defense, federal funding for embryonic stem cell research and space. The only thing this article lacks is enough detail to see where either or both men might be weaseling. Because--they're politicians--they're going to weasel.
It is starting to look like, for the American scientific community, either candidate would be an improvement over our current situation.
DNA "Tattoos" Link Adult, Daughter Stem Cells in Planarians
sea-maid submitted, created time 3 weeks 17 hours (www.sciencedaily.com)
The title of this article is poetic, but it could stand to be better organized. The authors refer to a certain method of DNA identification as a "tattoo," but don't immediately say what it is. One has to dig through the repetitive and error-strewn paragraphs before one finds this:
"the researchers devised methods to detect specific differences in gene expression in the BrdU-labeled cells. The researchers identified 259 genes associated with the stem cells and their daughters
sea-maid submitted, created time 1 month 1 week (www.nature.com)
Observers could be forgiven for thinking they had spotted a phoenix rising from the ashes of Advanced Cell Technology (ACT) earlier this week. The Los Angeles, California-based company, which is devoted to turning human embryonic stem cells into therapies, had been reported on the verge of extinction last month after it told the U.S. Securities and Exchange Commission that it would run out of money on 31 July
A natural reprogramming system
sea-maid submitted, created time 1 month 1 week (www.nature.com)
In fruit flies--and presumably other pupating insects--specialized cells revert to multipotency as the larva prepares to transform into an adult. We had thought that the differentiated larval cells simply died during this process, and many of them do, but it does seem that some can regain some pluripotency.
The way they figured this out is particularly vivid. By modifying the cells in the larvae's tracheae to glow green, researchers were able to track their destinations and daughter cells.
We already knew that some human cells were able to perform similar feats
New mouse stem cell is just like ours
sea-maid submitted, created time 1 month 2 weeks (www.newscientist.com)
The discovery of a mouse embryonic stem cell that is a near-perfect match to human cells may speed research in new treatments for injury and disease.
Taking cells from mouse embryos at later stages--epiblasts instead of blastomeres--seems to prevent them from developing the traits that make them so very different from human cell lines. This has many scientists pondering the evolutionary differences between humans and mice, but the real kicker seems to be that primate stem cell lines are much more difficult to culture than lines made from other species
Stem cells from menstrual blood save limbs
sea-maid submitted, created time 1 month 2 weeks (www.newscientist.com)
Stem cells derived from human menstrual blood have, in mice, prevented limbs with restricted blood flow from withering. Trials in humans facing amputations are expected to start next year.
First red blood cells grown in the lab
sea-maid submitted, created time 1 month 2 weeks (www.newscientist.com)
Blood donations may one day be a thing of the past thanks to the creation of the first functional red blood cells grown in the lab. The cells were grown from human embryonic stem cells (ESCs).
When the past catches up with the present
sea-maid submitted, created time 1 month 2 weeks (www.nature.com)
Oversight committees face tough decisions after an analysis questions whether certain cell lines meet standards of informed consent. If not, then the number of stem cell lines that U.S. scientists may study with federal funding may drop from twenty-one to sixteen.
Newly discovered molecular switch helps decide cell type in early embryo development
sea-maid submitted, created time 1 month 3 weeks (www.eurekalert.org)
Researchers have discovered a central molecular switch in fruit fly embryos that opens new avenues for studying the causes of birth defects and cancer in humans. Writing about their study in the Aug. 12 Developmental Cell, scientists at Cincinnati Children's Hospital Medical Center determined the switch to be a main tuning mechanism for instructing cells whether to form sensory nerves or blood cells in different parts of the body.
Induced stem cell lines may soon be available from Harvard
Darkfrog submitted, created time 1 month 4 weeks (sciencenow.sciencemag.org)
A few weeks ago, we talked about how researchers had been able to take a cell from an ALS patient and develop a working, research-quality pluripotent cell line. Well the next step has been taken.
I've been saying that induced pluripotent stem cells might become the preferred research model (over embryonic stem cells), but only if they became easier to obtain than embryonic stem cells. It looks as though that might happen soon. The Harvard Stem Cell Institute is dedicating an iPS core lab
Induced stem cells become research model for ALS
Darkfrog submitted, created time 2 months 5 days (sciencenow.sciencemag.org)
Induced stem cells are coming into their own as a research model. Scientists at Harvard and Columbia have created a culture of motor cells from the skin of a patient known to be afflicted with amyotropic lateral sclerosis, also known as Lou Gherig's disease.
The patient has a rare form of ALS that is known to be caused by an inherited mutation. This represents only 2% of ALS patients. This may be significant because critics claim that partial replicants of the patient's nerve cells will be of little use as research models
Consent issues restrict stem-cell use and research
sea-maid submitted, created time 2 months 1 week (www.nature.com)
Some researchers in Stanford University are told that around one-quarter of the human embryonic stem-cell lines eligible for U.S. government funding are now off-limits because of ethical concerns. The university is concerned that some of the women who donated the embyros that were used to generate the line might not have been fully informed of how they would be used.
The consent forms that the women signed were retrieved and it was found that none of them met Standford's guidelines exactly and some of them were way off the mark
Stem cell meeting 2008: complications for induced pluripotent stem cells
sea-maid submitted, created time 2 months 1 week (www.nature.com)
This year's meeting of the International Society for Stem Cell Research in Philadelphia, Pennsylvania, included a jam-packed session on the standards and methodologies of creating induced pluripotent stem cells. But although excitement around advances in reprogramming somatic cells shows no signs of abating, new ideas regarding the field are surfacing.
One announcement in particular may have consequences for induced pluripotent stem cells: It seems that ever reprogrammed cells can retain some echoes of their differentiated states, which researchers have nicknamed "cellular memory
Embryonic stem cells answer questions about breast cancer
sea-maid submitted, created time 2 months 1 week (www.nature.com)
Mutations in the BRCA1 and BRCA2 genes dramatically increase a woman's risk of breast cancer, and some women consider genetic screening in the hopes of earlier detection and treatment. Commercial tests can detect common variants associated with risk, but many mutations are unclassified
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