Secretion of pleiotrophin stimulates breast cancer progression through remodeling of the tumor microenvironment

bioman submitted, created time 1 year 6 months (www.pnas.org)

Pleiotrophin (PTN, Ptn) is an 18-kDa secretory cytokine expressed in many breast cancers; however, the significance of Ptn expression in breast cancer has not been established. We have now tested three models to determine the role of inappropriate expression of Ptn in breast cancer

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