Metabolic correlates of subthalamic nucleus activity in Parkinson's disease

kavin submitted, created time 8 months 25 minutes (www.ncbi.nlm.nih.gov)

In this paper, the authors scanned 17 PD patients with (18)F-fluorodeoxyglucose (FDG) PET to measure resting glucose metabolism before the implantation of STN deep brain stimulation electrodes. The findings suggest that the functional pathways associated with motor disability in PD are linked to the STN firing rate. These pathways are likely to mediate the clinical benefit that is seen following targeted STN interventions for this disease.

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