Effectiveness of Olanzapine, Quetiapine, and Risperidone in Patients With Chronic Schizophrenia After Discontinuing Perphenazine: A CATIE Study

alpha submitted, created time 1 year 9 months (ajp.psychiatryonline.org)

"The relative effectiveness of newly started antipsychotic drugs for individuals with schizophrenia may depend on multiple factors, including each patient’s previous treatment response and the reason for a new medication trial. This randomized, double-blind study compared olanzapine, quetiapine, and risperidone in patients who had just discontinued the older antipsychotic perphenazine. "

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Altruism is associated with an increased neural response to agency

nomad submitted, created time 1 year 10 months (www.nature.com)

Although the neural mechanisms underlying altruism remain unknown, empathy and its component abilities, such as the perception of the actions and intentions of others, have been proposed as key contributors. Tasks requiring the perception of agency activate the posterior superior temporal cortex (pSTC), particularly in the right hemisphere. Here, we demonstrate that differential activation of the human pSTC during action perception versus action performance predicts self-reported altruism.

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Becare of the angiotensin II type 1 receptor : it can blockade attenuates TGF- –induced failure of muscle regeneration in multiple myopathic states

DNA2004 submitted, created time 1 year 10 months (www.nature.com)

Skeletal muscle has the ability to achieve rapid repair in response to injury or disease1. Many individuals with Marfan syndrome (MFS), caused by a deficiency of extracellular fibrillin-1, exhibit myopathy and often are unable to increase muscle mass despite physical exercise. Evidence suggests that selected manifestations of MFS reflect excessive signaling by transforming growth factor (TGF)- (refs. 2,3)

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Superbowl Ads Stimulate Threat Response

Darkfrog submitted, created time 1 year 11 months (www.sciam.com)

"The most ineffective ad was from Honda, which showed participants were less engaged during the ad than they were when they looked at a blank screen." Heavens, this made me laugh. A review of Superbowl ads in Scientific American. Let's see how much money they wasted this year.

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