MedUnion submitted, created time 1 year 8 months (www.mupnet.com)

Recent studies have revealed that a glycolytic enzyme, enolase (ENO), is involved in many different physiological and pathophysiological conditions. ENO can be detected in many prokaryotic and eukaryotic cells, and is localized in cytoplasm, cell surface and nucleus of various mammalian cells to possibly mediate distinct functions. The surface ENO acts as a plasminogen-binding receptor. Upon cleavage by plasminogen activator, plasminogen is converted to plasmin that can activate collagenase and degrade fibrin and several extracellular matrix proteins

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