Articles with the keyword:
7

Hope of insulin cell transplant

sea-maid submitted, created time 2 days 4 hours (news.bbc.co.uk)

Scientists working towards pancreatic cell transplants as a cure for diabetes have taken the first step to getting around the problem of immune rejection.

10

Cancer drug effectively treats transplant rejections

sea-maid submitted, created time 1 week 4 days (esciencenews.com)

University of Cincinnati (UC) researchers have discovered a new therapy for transplant patients, targeting the antibody-producing plasma cells that can cause organ rejection.

9

Genetic engineering makes pig organs ready for humans at last?

sea-maid submitted, created time 1 month 1 week (www.newscientist.com)

In the not too distant future, a person in need of a heart transplant could be offered a pig's organ. That's the hope of a group that met in China last week to agree global guidelines for the first clinical trials of "xenotransplants."

There have been some serious problems that scientists have had to overcome. For example, porcine endogenous retroviruses, or PERVs, are one major concern. These are chunks of viral DNA incorporated into the pig genome. There are fears that these viruses could reawaken if they are transported into an unfamiliar body

12

Brain implant allows mute man to speak

sea-maid submitted, created time 1 month 2 weeks (www.nature.com)

An electrode implanted into the brain of a man with locked-in syndrome has enabled him to use a speech synthesizer to produce vowel sounds as he thinks them. The same team is now working on a chip that can also produce consonants.

Locked-in syndrome is a type of paralysis in which patients are unable to voluntarily move anything but their eyelids. However, they are fully conscious

12

Stem Cells Spawn First Drug-Free Windpipe Transplant

sea-maid submitted, created time 1 month 2 weeks (www.bloomberg.com)

Doctors operating on a 30-year-old Colombian woman restored her ability to breathe freely with the world's first transplanted windpipe specially treated to prevent organ rejection.

The airway connecting Claudia Castillo Sanchez's left lung to her windpipe collapsed after a persistent tuberculosis infection, leaving her short of breath and unable to perform routine daily activities. Efforts to prop it open failed, leaving Spanish doctors two options: remove the lung or replace the airway using an experimental technique tried only in animals

10

Tissue engineering triumph: Doctors transplant a trachea made from the patient's own stem cells

Darkfrog submitted, created time 1 month 2 weeks (www.lancet.com)

The medical journal Lancet has just announced that doctors have performed the first successful trachea transplant using a trachea crafted from the patient's own stem cells. The New York Times is hailing this as a revolutionary step in regenerative medicine. The surgery took place in Barcelona this past June. Researchers from universities in Spain, Britain and Italy collaborated on the preparation. The patient's original trachea--actually one of her bronchi--had been damaged by severe tuberculosis.

Prof

13

Neurodegenerative disease: Giving survival a boost

sea-maid submitted, created time 1 month 2 weeks (www.nature.com)

Although it is the selective death of motor neurons that ultimately causes the symptoms of amyotrophic lateral sclerosis (ALS), the disease also renders other spinal cord cells, including astrocytes, dysfunctional. Maragakis and colleagues have now shown that the replacement of damaged astrocytes through precursor cell transplantation might be a useful therapeutic strategy for ALS.

The authors transplanted glial restricted precursors (GRPs) into the grey matter of the spinal cord in a transgenic rat model of ALS

14

Stem Cells with Potential to Regenerate Injured Liver Tissue Identified

sea-maid submitted, created time 1 month 3 weeks (www.sciencedaily.com)

A novel protein marker has been found that identifies rare adult liver stem cells, whose ability to regenerate injured liver tissue has the potential for cell-replacement therapy. For the first time, researchers at the University of Pennsylvania School of Medicine led by Linda Greenbaum, MD, Assistant Professor of Medicine in the Division of Gastroenterology, have demonstrated that cells expressing the marker can differentiate into both liver cells and cells that line the bile duct.

This discovery could have serious implication for transplants and regenerative medicine

8

Bone marrow transplant suppresses AIDS in patient

sea-maid submitted, created time 1 month 3 weeks (www.reuters.com)

A bone marrow transplant using stem cells from a donor with natural genetic resistance to the AIDS virus has left an HIV patient free of infection for nearly two years, German researchers.

The patient, an American living in Berlin, was infected with the human immunodeficiency virus that causes AIDS and also had leukemia. The best treatment for the leukemia was a bone marrow transplant, which takes the stem cells from a healthy donor's immune system to replace the patient's cancer-ridden cells.

Dr

11

French Try Plane Technology in Artificial Heart

sea-maid submitted, created time 2 months 1 week (www.time.com)

In the race to build a better artificial heart, French scientists have turned to technology from satellites and airplanes to create a heart that they say responds better to the human body. So far, the new device, shown at a news conference in Paris on Monday, has only been tested in animals. Its makers hope it might one day help people survive without needing a human heart transplant.

The maker of this artificial heart is a subsidiary of the European Aeronautic and Space Defense Company (EADS), but this isn't a matter of fluid dynamics

8

The Artificial Heart: Not Just a Pump

sea-maid submitted, created time 3 months 2 weeks (www.sciam.com)

In the late 1970's, both the medical community and the public were filled with optimism about the possibilities of medical science in general and the artificial heart project in particular. By the 1980's, the pendulum had swung the other way completely. This article is a colorful and well-written treatment of what happened in between to cause this change ...and what is happening now to bring it back.

8

Retinal transplants bear threefold fruit

Darkfrog submitted, created time 3 months 4 weeks (www.nature.com)

A formerly clinically blind woman's vision improved from 20/800 to 20/160--from one-fortieth of ordinary vision to one-eighth--after receiving donated retina. Six months after the operation, the started noticing the pendulum in her grandfather clock. For years, she found that she could read large-print books and emails and returned to her hobbies, knitting and sewing. Now, six years after her operation, her vision is fading, but it is still better than it was before the operation

8

Growing blood in a dish

sea-maid submitted, created time 5 months 2 weeks (www.nature.com)

Developing a way to reliably produce hematopoietic stem cells is a bloody tough problem. Unlike most tissues, cells of the hematopoietic system emerge from several embryonic sites and then circulate through the body. This mobility has perplexed researchers, who hope that mimicking the in vivo environment will help them culture these stem cells. Now, two British research teams report in Cell Stem Cell their complementary techniques for isolating these cells. These methods could form the lifeblood of creating easier alternatives to bone marrow transplantation.

8

Cellular Islet Autoimmunity and Islet Cell Transplantation

jerry submitted, created time 6 months 5 days (www.plosone.org)

Islet cell transplantation can cure type 1 diabetes (T1D), but only a minority of recipients remains insulin–independent in the following years. They tested the hypothesis that allograft rejection and recurrent autoimmunity contribute to this progressive loss of islet allograft function.

Methodology/Principal Findings:
Twenty-one T1D patients received cultured islet cell grafts prepared from multiple donors and transplanted under anti-thymocyte globulin (ATG) induction and tacrolimus plus mycophenolate mofetil (MMF) maintenance immunosuppression

10

The military AFIRMs regenerative medicine

Darkfrog submitted, created time 6 months 1 week (www.popsci.com)

As of this past March, thirty different research institutions have joined to become the Armed Forces Institute of Regenerative Medicine (AFIRM). With $250-million in funding, they plan to expand ideas like the "pixie dust" limb regrowth method that was mentioned on DiscoveR8 a few months back. Most interestingly, there are plans for a handheld spritzer that would spray keratinocytes directly onto burns and wounds.

I followed the links to this one. A few blogs wrote articles based on this one, but focusing on just the burn sprayer, which they've nicknamed the "stem cell gun

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