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Blood thinners like aspirin may help fight cancer
sumsung submitted, created time 9 months 4 weeks (www.reuters.com)
Blood-thinning drugs such as aspirin may help fight cancer by denying shelter to wandering tumor cells, U.S. researchers reported on Friday. Experiments in mice showed that combining aspirin with an experimental anti-clotting drug slowed the growth and spread of breast and melanoma tumors. 


Elevated level of SUMOylated IRF-1 in tumor cells interferes with IRF-1-mediated apoptosis
stephen submitted, created time 1 year 2 months (www.pnas.org)
SUMOylation of transcription factors often attenuates transcription activity. This regulation of protein activity allows more diversity in the control of gene expression. Interferon regulatory factor-1 (IRF-1) was originally identified as a regulator of IFN-α/β, and its expression is induced by viral infection or IFN stimulation. 
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