MedUnion submitted, created time 10 months 3 weeks (www.mupnet.com)

AIM: Cholangiocarcinoma (CC) is a devastating neoplasm usually hard to get diagnosed in the early stage due to the unfavorable anatomic location. The currently used tumor markers like CEA and CA 19-9 are not always helpful because of the unsatisfactory sensitivities and specificities. In this study, surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF-MS) was used to identify the potential biomarker for CC

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