Immunosuppressive Drug Merits Fungal Warning

jerry submitted, created time 2 months 2 weeks (health.usnews.com)

The Food and Drug Administration has asked the manufacturers of Humira, Cimzia, Enbrel, and Remicade—which belong to a class of medications known as tumor necrosis factor alpha blockers (TNF-alpha blockers)—to strengthen the warning for risk of fungal infection.

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Efficient replication of pneumonia virus of mice (PVM) in a mouse macrophage cell line

annatto submitted, created time 1 year 5 months (www.virologyj.com)

"Pneumonia virus of mice (PVM; family Paramyxoviridae, subfamily Pneumovirinae) is a natural respiratory pathogen of rodent species and an important new model for the study of severe viral bronchiolitis and pneumonia. However, despite high virus titers typically detected in infected mouse lung tissue in vivo, cell lines used routinely for virus propagation in vitro are not highly susceptible to PVM infection

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