Flu season worst in years, vaccine ineffective

siemens submitted, created time 7 months 2 days (edition.cnn.com)

This year's flu season has shaped up to be the worst in three years, partly because the vaccine didn't work well against the viruses that made most people sick, health officials said Thursday.

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Immunizations Are Discontinued in Two HIV Vaccine Trials

june submitted, created time 1 year 1 month (www.nlm.nih.gov)

An independent Data and Safety Monitoring Board (DSMB) met this week to review interim data from a large, international HIV vaccine clinical trial known as the STEP study — also referred to as the HVTN 502 or Merck V520-023 study. The clinical trial, which began enrolling volunteers in December 2004, is co-sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), and the pharmaceutical company Merck & Co. Inc., which also developed and supplied the candidate vaccine

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China should have probed "bad vaccine" cases

Reviver submitted, created time 1 year 3 months (www.reutershealth.com)

A World Health Organisation official said on Frida, china should have investigated why some children suffered severe brain damage after being vaccinated against Japanese encephalitis a few years ago.

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Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major

penguin submitted, created time 1 year 5 months (www.nature.com)

Here, using multiparameter flow cytometry to assess the immune responses after immunization, we show that the degree of protection against Leishmania major infection in mice is predicted by the frequency of CD4+ T cells simultaneously producing interferon-gamma, interleukin-2 and tumor necrosis factor. Notably, multifunctional effector cells generated by all vaccines tested are unique in their capacity to produce high amounts of interferon-gamma

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