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12

New Strategy for Broad-Spectrum Anti-viral Drugs Developed

piggy submitted, created time 1 month 5 days (www.sciencedaily.com)

Bavituximab, an anti-viral drug developed by UT Southwestern Medical Center researchers, shows promise as a new strategy to fight viral diseases, including potential bioterrorism agents.

In a study appearing in the December issue of Nature Medicine, groups of guinea pigs infected with a virus similar to Lassa fever virus recovered from the fatal disease when treated with bavituximab alone or in combination with a common anti-viral medication. Bavituximab treatment also cured mice infected with cytomegalovirus, an opportunistic infection that afflicts transplant and AIDS patients.

Dr

12

Common Cold Virus Came from Birds About 200 Years Ago, Study Suggests

piggy submitted, created time 1 month 1 week (www.sciencedaily.com)

A virus that causes cold-like symptoms in humans originated in birds and may have crossed the species barrier around 200 years ago, according to a new article published in the Journal of General Virology. Scientists hope their findings will help us understand how potentially deadly viruses emerge in humans.

"Human metapneumovirus may be the second most common cause of lower respiratory infection in young children. Studies have shown that by the age of five, virtually all children have been exposed to the virus and re-infections appear to be common," said Professor Dr Fouchier

9

Virus Gets a Taste of Its Own Medicine

jerry submitted, created time 4 months 4 weeks (sciencenow.sciencemag.org)

Little more than protein capsules chock-full of genetic material, viruses barely rank among the living. Yet like people, at least one virus can catch a virus--the viral equivalent of coming down with the flu. This "flu" virus impairs the host virus's ability to grow and reproduce, a research team studying the largest known viruses reports.

Viruses are tiny biological hijackers that cause diseases that include the common cold, the flu, chickenpox, and AIDS. They infect animals, plants, and microorganisms and use their host's cellular machinery to make copies of themselves

14

Beijing reports first child virus death

sea-maid submitted, created time 7 months 3 weeks (ap.google.com)

This study reports the first death from the hand, foot and mouth disease virus that has sickened tens of thousands of children across the country and killed at least forty-two people.

10

China orders heightened efforts to stop deadly virus

kavin submitted, created time 8 months 5 days (hosted.ap.org)

Before long, the outbreak of enterovirus 71, a type of hand, foot and mouth disease that children are susceptible to in Fuyang city has been paid close attention to, which is another headache for the communist government as it prepares for the Beijing Olympics already tarnished by an uprising among Tibetans and an international torch relay disrupted by protests. And China's Health Ministry ordered heightened efforts to stem the spread of infectious diseases Saturday following an outbreak of a virus

6

Study proposes new theory of how viruses may contribute to cancer

davis submitted, created time 1 year 2 months (www.eurekalert.org)

A study published in the Oct. 24 issue of PLoS ONE suggests that viruses may contribute to cancer by causing excessive death to normal cells while promoting the growth of surviving cells with cancerous traits. The University of Pittsburgh Cancer Institute researchers suggest that viruses may act as forces of natural selection by wiping out normal cells that support the replication of viruses, leaving behind those cells that have acquired defects in their circuitry.

7

'Jumping genes' could make for safer gene delivery system

william submitted, created time 1 year 3 months (www.eurekalert.org)

To move a gene from point A to point B, scientists and gene therapists have two proven options: a virus, which can effectively ferry genes of interest into cells, and a plasmid, an engineered loop of DNA that can do the same thing, albeit usually only on a short-term basis.

11

Penn Veterinary Medicine report new strategy to create genetically modified animals

kitty submitted, created time 1 year 3 months (www.eurekalert.org)

Researchers at Penn Vet have demonstrated a new strategy for genetic modification of large animals by employing a virus that transfers genetic modifications to male reproductive cells, which passes naturally to offspring. Scientists at the Center for Animal Transgenesis and Germ Cell Research at Penn introduced adeno-associated virus to germline stem cells in goats and mice.

6

Scientists learn structure of enzyme in unusual virus

kitty submitted, created time 1 year 3 months (news.uns.purdue.edu)

Biologists have determined the three-dimensional structure of an unusual viral enzyme that is required in the assembly of new viruses.

7

New viruses to treat bacterial diseases -- 'My enemies' enemy is my friend'

sumsung submitted, created time 1 year 4 months (www.eurekalert.org)

Viruses found in the River Cam in Cambridge, famous as a haunt of students in their punts on long, lazy summer days, could become the next generation of antibiotics, according to scientists speaking today (Monday Sept. 3 2007) at the Society for General Microbiology's 161st Meeting at the University of Edinburgh, UK, which runs from Sept. 3-6 2007.

10

Carnegie Mellon scientists find key HIV protein makes cell membranes bend more easily

sumsung submitted, created time 1 year 5 months (www.eurekalert.org)

Carnegie Mellon University scientists have made an important discovery that helps to explain why HIV enters immune cells with ease. They found that after HIV docks onto a host cell, it dramatically lowers the energy required for a cell membrane to bend, making it easier for the virus to infect immune cells.

5

Universal flu vaccine being tested on humans

bianjie submitted, created time 1 year 5 months (www.eurekalert.org)

A universal influenza vaccine that has been pioneered by researchers from VIB and Ghent University is being tested for the first time on humans by the British-American biotech company Acambis. This vaccine is intended to provide protection against all "A" strains of the virus that causes human influenza, including pandemic strains.

5

Researchers discover key mechanism to emergence of deadly strep bacteria

bianjie submitted, created time 1 year 5 months (www.eurekalert.org)

Serious strep infections have risen dramatically in the last three decades, and this increase is largely attributed to the spread around the globe of a single strain of strep known as the invasive M1T1 clone. Researchers at the UCSD School of Medicine and the University of Wollongong in Australia have discovered that, 30 years ago, a virus infected the strep bacteria -- creating a deadly strain of "flesh-eating" bacteria.

5

Libya resolves to execute Bulgarian AIDS workers

Hecate submitted, created time 1 year 5 months (www.nytimes.com)

Today, the Libyan Supreme Court has upheld the death sentences of five Bulgarian nurses and one Palestinian doctor who were accused of deliberately infecting a number of Libyan children with HIV in 1998. They were tried, convicted, and lawfully sentenced to death. However, a 2003 investigation by leading AIDS experts indicates that the children's infections are due to unsanitary hospital conditions and not wrongdoing on the part of the doctor and nurses. The E.U. and U.S. have repeatedly appealed to Libya to free the six accused, but it is no use

7

MIT, BU team builds viruses to combat harmful 'biofilms'

bianjie submitted, created time 1 year 5 months (web.mit.edu)

In one of the first potential applications of synthetic biology, an emerging field that aims to design and build useful biomolecular systems, researchers from MIT and Boston University are engineering viruses to attack and destroy the surface "biofilms" that harbor harmful bacteria in the body and on industrial and medical devices.

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