Effect of 50 000 IU vitamin A given with BCG vaccine on mortality in infants in Guinea-Bissau

sea-maid submitted, created time 6 months 3 weeks (www.bmj.com)

Vitamin A supplementation reduces mortality in older children, but a global recommendation of high dose supplementation for all newborn infants may not contribute to better survival, say the authors of this randomised controlled trial. The accompanying editorial says that benefit depends on the setting, baseline infant mortality, and vitamin A deficiency.

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Papaya genome project bears fruit

Genetic discovery can boost the provitamin A content of Africa's maize

jane2007 submitted, created time 11 months 2 weeks (www.news.cornell.edu)

A new discovery could change health disorders caused by lack of provitamin A. Using genetic and statistical tools, researchers have identified a set of genetic variants in maize that accounts for levels of vitamin A precursors among varieties.

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By Keeping Vitamin A Active Drug Slows Prostate Tumor Growth

june submitted, created time 1 year 2 months (www.medicalnewstoday.com)

A novel compound that blocks the breakdown of retinoic acid, derived from vitamin A, is a surprisingly effective and "promiscuous" agent in treating animal models of human prostate cancer, say investigators from the University of Maryland, Baltimore (UMB).

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Folic acid could protect against strokes

captainclaw submitted, created time 1 year 7 months (www.newscientist.com)

Folic acid supplements can reduce the risk of stroke by 30%, according to a review of eight studies involving nearly 17,000 participants.The new findings will add fuel to growing calls for the B vitamin to be routinely added to flour or bread - to protect against birth defects - in countries such as the UK where this is not already practice.

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Vitamins in control of lymphocyte migration

badboy submitted, created time 1 year 9 months (www.nature.com)

Localized vitamin metabolism by dendritic cells generates homing cues that direct lymphocytes to specific tissues. Gut tropism is linked to vitamin A and now epidermal skin tropism is linked to vitamin D processing.

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Never a Controversy for Vitamin A

Cassidy submitted, created time 1 year 11 months (sciencenow.sciencemag.org)

Vitamin A is no ordinary dietary supplement, which was carried through the blood
and delivered to tissues by a molecule called retinol-binding protein (RBP). Just how vitamin A gets into cells, however, has remained a mystery. Researchers took 3 decades
to to isolate a receptor, but always empty, which lead to a controversy among researchers, some researchers thought the receptor didn?.t exsit. Biochemist Hui Sun persist that it was out there. He took experiment to prove the existence of receptor by a crosslinker. At last, he succeeded, and get the right receptor, called STRA6

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