Antioxidants fail to prevent prostate cancer

sea-maid submitted, created time 4 weeks 1 day (www.sciencenews.org)

Despite much hope generated by earlier studies, vitamins C and E and the element selenium have failed to reduce the incidence of prostate cancer. The disappointing news from two huge trials is reported online December 9 in the Journal of the American Medical Association.

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New Life for a Discredited Treatment?

sea-maid submitted, created time 4 months 4 weeks (sciencenow.sciencemag.org)

The long-dormant debate over vitamin C's usefulness for cancer therapy may be about to reignite. Researchers have found that injecting mice with high doses of the vitamin staved off tumor growth. The findings could upend the established view that vitamin C is useless as a cancer treatment.

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Acute and chronic effects of vitamin C on endothelial fibrinolytic capacity

kavin submitted, created time 7 months 1 week (www.ncbi.nlm.nih.gov)

The authors determined the effects of acute intra-arterial vitamin C administration and chronic oral vitamin C supplementation on the capacity of the endothelium to release t-PA in overweight and obese adults. Their results indicate that the antioxidant vitamin C favorably affects the capacity of the endothelium to release t-PA in overweight/obese adults. Daily vitamin C supplementation represents an effective lifestyle intervention strategy for improving endothelial fibrinolytic regulation in this at-risk population.

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Study shows vitamin C is essential for plant growth

richard submitted, created time 1 year 3 months (www.eurekalert.org)

Scientists from the University of Exeter and Shimane University in Japan have proved for the first time that vitamin C is essential for plant growth. This discovery could have implications for agriculture and for the production of vitamin C dietary supplements.

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Scientists Find Missing Link to Understand How Plants Make Vitamin C

BIOBOSS submitted, created time 1 year 8 months (dms.dartmouth.edu)

Vitamin C is possibly the most important small molecule whose biosynthetic pathway remained a mystery. That is until now. A group of Dartmouth and UCLA researchers, who normally work on genes involved in aging and cancer in animals, discovered the last piece of the puzzle, they report in a study published online April 26 in the Journal of Biological Chemistry.

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Fruit proves better than vitamin C alone

julie submitted, created time 1 year 8 months (www.bioedonline.org)

"If you're in the market for an antioxidant to keep your body young and healthy, new research suggests you'd be much better off with oranges than vitamin C tablets. "

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Obesity linked to growth of cancer

medal submitted, created time 1 year 8 months (www.biopeer.com)

"Researchers from the University of Glasgow have discovered that fat negates the anti-cancer properties of vitamin C. Through laboratory experiments, they detected that vitamin C or ascorbic acid cleared the stomach of the cancer-causing compound, which was a result of saliva and food combining with the acid in the stomach. However, the ascorbic acid could no longer fight the cancer-causing compound when fat was added to the combination. The researchers feel that their findings emphasize the value of a balanced diet with a low intake of fat. "

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Fat overrides effects of vitamin C

fiona submitted, created time 1 year 9 months (www.biologynews.net)

"Fats in our stomach may reduce the protective effects of antioxidants such as vitamin C. Scientists at the University of Glasgow found that in the presence of lipid the ability of antioxidants, such as ascorbic acid (the active component of vitamin C), to protect against the generation of potential cancer-forming compounds in the stomach is less than when no lipids are present

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Novel aspects of vitamin C: how important is glypican-1 recycling?

amanda submitted, created time 1 year 9 months (www.sciencedirect.com)

"The reduced form of vitamin C, ascorbic acid, is well known for its function as an antioxidant and as a protective agent against scurvy. However, many recent studies indicate other functions for vitamin C in mammalian cells. Novel findings provide possible explanations for observed beneficial effects of a high intake of vitamin C on cell growth, gene transcription, host resistance to infection, uptake of polyamines and clearance of misfolded proteins

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