HWI scientist first in world to unravel structure of key breast cancer target enzyme
piggy submitted, created time 21 hours 48 minutes (www.eurekalert.org)
The molecular details of Aromatase, the key enzyme required for the body to make estrogen, are no longer a mystery thanks to the structural biology work done by the Ghosh lab at the Hauptman-Woodward Medical Research Institute (HWI) in Buffalo, New York. Dr. Debashis Ghosh's solution of the three-dimensional structure of aromatase is the first time that scientists have been able to visualize the mechanism of synthesizing estrogen 
Control of blood vessels a possible weapon against obesity
piggy submitted, created time 21 hours 48 minutes (www.eurekalert.org)
Mice exposed to low temperatures develop more blood vessels in their adipose tissue and metabolize body fat more quickly, according to a new study from Karolinska Institutet. Scientists now hope to learn how to control blood vessel development in humans in order to combat obesity and diabetes.
The growth of fat cells and their metabolism depend on oxygen and blood-borne nutrients. A possible way to regulate the amount of body fat – in order, for instance, to combat obesity – can therefore be to affect the development of blood vessels in the adipose tissue
piggy submitted, created time 1 day 2 hours (www.eurekalert.org)
The enzyme machine that translates a cell's DNA code into the proteins of life is nothing if not an editorial perfectionist.
Johns Hopkins researchers, reporting this week in Nature, have discovered a new proofreading step during which the suite of translational tools called the ribosome recognizes errors, just after making them, and definitively responds by hitting its version of a delete button
Pneumococcal Vaccine Does Not Appear to Protect Against Pneumonia
sea-maid submitted, created time 1 day 10 hours (www.sciencedaily.com)
Commonly used pneumococcal polysaccharide vaccines do not appear to be effective for preventing pneumonia, found a study by a team of researchers from Switzerland and the United Kingdom.
Muscle Cells May Hold a Key to Repairing Young Hearts
sea-maid submitted, created time 1 day 10 hours (www.washingtonpost.com)
No, this isn't a reminder that today -- the 12th day of Christmas -- is the traditional day to pack away the tree ornaments. These brilliant orbs are actually a layer of fluorescently stained muscle cells designed to encourage the growth of stem cells that may one day replace pacemakers in children and keep young hearts beating on time, according to Doug Cowan, an assistant professor of anesthesia at Children's Hospital Boston.
Hepatitis A vaccine gives long-lasting protection
sea-maid submitted, created time 1 day 10 hours (health.yahoo.com)
Hepatitis A infections, usually transmitted via contaminated food, can cause debilitating illness, but protection afforded by the hepatitis A vaccine last more than a decade, a new study shows.
Bulimia Tied to Brain Differences
sea-maid submitted, created time 1 day 10 hours (www.webmd.com)
Women with bulimia nervosa may be particularly impulsive because of their brain activity patterns, a new study shows.
The study, published in January's edition of the Archives of General Psychiatry, included twenty women with bulimia and twenty women without bulimia. The women's ages and BMI were similar in both groups.
Each woman had her brain scanned using functional magnetic resonance imaging (fMRI) while she took a brain function test
Study raises hope for obesity treatment
sea-maid submitted, created time 1 day 10 hours (news.yahoo.com)
U.S. researchers may have found an obesity treatment that unlocks the fat-fighting promise of leptin, an appetite-suppressing hormone once hailed as the answer to the battle of the bulge.
Old gastrointestinal drug slows neurodegenerative diseases
sea-maid submitted, created time 1 day 10 hours (www.eurekalert.org)
Recent animal studies have shown that clioquinol – an eighty-year-old drug once used to treat diarrhea and other gastrointestinal disorders – can reverse the progression of Alzheimer's, Parkinson's and Huntington's diseases. Scientists, however, had a variety of theories to attempt to explain how a single compound could have such similar effects on three unrelated neurodegenerative disorders.
Researchers at McGill University have discovered a dramatic possible new answer: According to Dr
Scrawny gene keeps stem cells healthy
piggy submitted, created time 1 day 20 hours (www.eurekalert.org)
Stem cells are the body's primal cells, retaining the youthful ability to develop into more specialized types of cells over many cycles of cell division. How do they do it? Scientists at the Carnegie Institution have identified a gene, named scrawny, that appears to be a key factor in keeping a variety of stem cells in their undifferentiated state. Understanding how stem cells maintain their potency has implications both for our knowledge of basic biology and also for medical applications. The results will be published in the January 9, 2009 print edition of Science
piggy submitted, created time 1 day 20 hours (www.sciencedaily.com)
NYU Langone Medical Center scientists and their collaborators at the Scripps Research Institute in La Jolla, California, have discovered an unexpected cause for the fatal seizures seen in mice with viral meningitis, an infection of the central nervous system, according to a study published in the journal Nature. The finding may lead to a new way of thinking about how the human immune system responds to viral diseases.
The NYU researchers, Michael L. Dustin, Ph.D., the Irene Diamond Professor of Immunology and Professor of Pathology at NYU School of Medicine, and Jiyun V. Kim, Ph.D
Hope of insulin cell transplant
sea-maid submitted, created time 2 days 10 hours (news.bbc.co.uk)
Scientists working towards pancreatic cell transplants as a cure for diabetes have taken the first step to getting around the problem of immune rejection.
Ohio State Studies Alzheimer's Vaccine Effectiveness
sea-maid submitted, created time 2 days 10 hours (media.www.thelantern.com)
Researchers at The Ohio State University Medical Center have begun studying the effects of a vaccine in slowing the onset of Alzheimer's disease or preventing it altogether.
sea-maid submitted, created time 2 days 11 hours (www.sciencemag.org)
Circumstantial evidence hints that the cytomegalovirus, a common herpes virus, may play a role in aggressive brain cancer, but big questions remain.
Viagra's other talents: Helping a signaling protein shield the heart from high blood pressure damage
sea-maid submitted, created time 2 days 11 hours (www.eurekalert.org)
Johns Hopkins and other researchers report what is believed to be the first direct evidence in lab animals that the erectile dysfunction drug sildenafil amplifies the effects of a heart-protective protein.
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