Cell's split personality is a major discovery into neurological diseases
piggy submitted, created time 10 months 2 days (www.eurekalert.org)
Researchers at the Université de Montreal (UdeM) and the Montreal Neurological Institute (MNI), McGill University have discovered that cells which normally support nerve cell (neuron) survival also play an active and major role in the death of neurons in the eye. The findings, published this week in The Journal of Neuroscience, may lead to more streamlined therapies for a variety of acute and chronic neurological disorders, including glaucoma and retinal artery occlusion 
Time (and PPAR-beta/delta) Heals All Wounds
piggy submitted, created time 11 months 1 week (www.sciencedaily.com)
Mammalian skin requires constant maintenance, but how do skin cells know when to proliferate and at what rate? In the March 23, 2009 issue of the Journal of Cell Biology, Nguan Soon Tan and colleagues reveal that skin fibroblasts use a protein called PPARβ/δ to make sure overlying epithelial cells don't proliferate too quickly. Their results highlight how communications between different cell types are critical to maintain the skin as a barrier against the outside world
Skin cancer study uncovers new tumor suppressor gene
piggy submitted, created time 11 months 1 week (www.eurekalert.org)
National Institutes of Health (NIH) researchers have identified a gene that suppresses tumor growth in melanoma, the deadliest form of skin cancer. The finding is reported today in the journal Nature Genetics as part of a systematic genetic analysis of a group of enzymes implicated in skin cancer and many other types of cancer.
The NIH analysis found that one-quarter of human melanoma tumors had mutations in genes coding for matrix metalloproteinase (MMP) enzymes
Penn biologists discover how silent mutations influence protein production
piggy submitted, created time 11 months 1 hour (www.eurekalert.org)
Biologists at the University of Pennsylvania have revealed a hidden code that determines the expression level of a gene, providing a way to distinguish efficient genes from inefficient ones. The new research, which involved creating hundreds of synthetic green-glowing genes, provides an explanation for how a cell "knows" how to make just the right amount of protein to maintain homeostasis yet not so much as to cause cell toxicity
Using Night Vision Technology To Learn More About Lymphatic System
piggy submitted, created time 10 months 2 days (www.sciencedaily.com)
The director of the new Center for Molecular Imaging at The University of Texas Health Science Center at Houston is using near-infrared night vision technology made famous by American soldiers in the First Gulf War to shed light on the lymphatic system.
While much is known about the blood system, Eva Sevick, Ph.D
'Happy hour' gene discovery suggests cancer drugs might treat alcoholism
sea-maid submitted, created time 9 months 2 weeks (www.eurekalert.org)
A class of drugs already approved as cancer treatments might also help to beat alcohol addiction. That's the conclusion of a discovery in flies of a gene, dubbed happyhour, that has an important and previously unknown role in controlling the insects' response to alcohol.
Cholesterol drug cuts amputation risk for diabetics
sea-maid submitted, created time 9 months 2 weeks (www.reuters.com)
The anti-cholesterol drug fenofibrate appears to reduce risks of amputation for diabetics by as much as 36 percent, a study has found.
Old seasonal flu antibodies target swine flu virus
sea-maid submitted, created time 9 months 2 weeks (www.nature.com)
Lab results could explain why young patients are hardest hit by current H1N1 strain.
Mutant Genes In High-risk Childhood Leukemias Identified
sea-maid submitted, created time 9 months 1 week (www.sciencedaily.com)
A research team has pinpointed a new class of gene mutations, which identify cases of childhood acute lymphoblastic leukemia (ALL) that have a high risk of relapse and death. The finding suggests specific drugs that could treat this high-risk leukemia subtype in children, particularly because such drugs are already in clinical trials for similar blood diseases in adults.
TB Vaccine Gets Its Groove Back
sea-maid submitted, created time 9 months 1 week (www.sciencedaily.com)
A team of Vanderbilt University Medical Center investigators has cracked one of clinical medicine's enduring mysteries – what happened to the tuberculosis vaccine. The once-effective vaccine no longer prevents the bacterial lung infection that kills more than 1.7 million people worldwide each year.
sea-maid submitted, created time 7 months 3 weeks (www.sciencedaily.com)
Plant roots provide the crops we eat with water, nutrients and anchorage. Understanding how roots grow and how hormones control that growth is crucial to improving crop yields, which will be necessary to address food security and produce better biofuels.
Gene Mutation Is Linked to Heart Muscle Disease
sea-maid submitted, created time 7 months 3 weeks (news.yahoo.com)
Gene mutations that cause heart muscle disease and chronic heart failure in some children and adults with dilated cardiomyopathy have been identified by researchers
Nanoparticles Turn Immune System Soldiers Against Tumor Cells
sea-maid submitted, created time 7 months 3 weeks (www.redorbit.com)
In a feat of trickery, Dartmouth Medical School immunologists have devised a Trojan horse to help overcome ovarian cancer, unleashing a surprise killer in the surroundings of a hard-to-treat tumor.
Acetaldehyde in Alcohol: "Hangover Chemical" May Be Overlooked Risk Factor for Cancer
piggy submitted, created time 11 months 2 weeks (www.sciencedaily.com)
New evidence by researchers at the Centre for Addiction and Mental Health (CAMH) and researchers in Germany shows that drinking alcohol is the greatest risk factor for acetaldehyde-related cancer. Heavy drinkers may be at increased risk due to exposure from multiple sources.
Acetaldehyde, also called ethanal, is ubiquitous in daily life in Ontario. Widely present in the environment, it is inhaled from the air and tobacco smoke, ingested from alcohol and foods, and produced in the human body during the metabolism of alcoholic beverages
Ticking of body's 24-hour clock turns gears of metabolism and aging
piggy submitted, created time 11 months 2 weeks (www.eurekalert.org)
All animals, including humans, have an internal 24-hour clock or circadian rhythm that creates a daily oscillation of body temperature, brain activity, hormone production and metabolism. Studying mice, researchers at Washington University School of Medicine in St. Louis and Northwestern University found how the biological circadian clock mechanism communicates with processes that govern aging and metabolism
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