132 Articles with the topic: Bioinformatics
The gold standard: Biodesign Institute researchers use nanoparticles to make 3-D DNA nanotubes
piggy submitted, created time 6 days 6 hours (www.eurekalert.org)
Arizona State University researchers Hao Yan and Yan Liu imagine and assemble intricate structures on a scale almost unfathomably small. Their medium is the double-helical DNA molecule, a versatile building material offering near limitless construction potential.
In the January 2, 2009 issue of Science, Yan and Liu, researchers at ASU's Biodesign Institute and faculty in the Department of Chemistry and Biochemistry, reveal for the first time the three-dimensional character of DNA nanotubules, rings and spirals, each a few hundred thousandths the diameter of a human hair 
Towards the Virtual Screening Technique: Trends and Updates
yarmoluk submitted, created time 2 months 6 days (www.otavachemicals.com)
One of the leading Ukrainian companies, OTAVA Ltd. develops its own virtual screening system.
New system citation system allows cross-disciplinary review. Is this the next h-index?
Darkfrog submitted, created time 2 months 2 weeks (www.nature.com)
Ordinarily, scientists use their h-index to determine whether their articles are up to snuff, citation-wise, and the system works well enough. Everyone accepts that it cannot be used across disciplines because overall citation rates are different. An aerospace paper that has twenty citations has made a huge impact. A developmental biology paper that has a hundred citations is skimming average.
A team out of Sapienza University in Rome has come up with a new system
Tissue sample suggests HIV has been infecting humans for a century
sea-maid submitted, created time 3 months 6 days (www.nature.com)
Tissue samples from the fifties and sixties, taken from patients living in Kinshasa (then Leopoldville) in the Democratic Republic of Congo indicate that HIV, which was first recognized in the 1980's. Researchers were able to pluck chinks of viral DNA from the crudely preserved samples. Comparing the levels of genetic variation allowed them to give an estimate of HIV-1's year of origin: 1908.
This does not show us how HIV crossed from chimpanzees into humans, but it does give us a better idea of where to look for the disease's origins.
Protein Kinase CK2: new perspectives of an old kinase
yarmoluk submitted, created time 3 months 2 weeks (www.discover8.com)
Protein Kinase CK2: new perspectives of an old kinase
Design of specific small molecules that are able to block (inhibit) function of macromolecular targets responsible for the development of certain disorder is the “classic” and most widely used approach in modern drug therapeutics, e.g., in cancer treatment
A new way to identify disease associated genes
jerry submitted, created time 3 months 2 weeks (www.biodatamining.org)
A new algorithm, which mines databases of tissue specificity, gene connectivity and disease association, has identified a new group of genes that interact with disease-causing genes and impact on disease outcomes.
sea-maid submitted, created time 3 months 3 weeks (www.sciencebase.com)
Studies have shown that social networking is a risk factor for catching a sexually transmitted disease (but only real-world social networking; LinkedIn is okay). However, this seems to be more of a result of an understanding of what a social network is than any Internet-induced change in the way people choose sexual partners. Sexually transmitted diseases are by definition (usually) transmitted along intimate social networks.
National parks spark population growth! ...human populations
Darkfrog submitted, created time 6 months 21 hours (sciencenow.sciencemag.org)
Despite what critics, proponents, common sense and a proportionate number of the planets 8-balls would have told us, national parks in developing countries are GOOD for people but BAD for animals.
It doesn't make sense on the surface. Opponents of national parks in poor areas have argued that people shouldn't be barred access to traditional hunting grounds, but demographic studies show that human population growth near park borders increases faster than in other places--it implies that people are moving there for the jobs and aid that go hand-in-hand with park placement
Computational Systems Analysis of Dopamine Metabolism
jerry submitted, created time 6 months 5 days (www.plosone.org)
A prominent feature of Parkinson's disease (PD) is the loss of dopamine in the striatum, and many therapeutic interventions for the disease are aimed at restoring dopamine signaling. Dopamine signaling includes the synthesis, storage, release, and recycling of dopamine in the presynaptic terminal and activation of pre- and post-synaptic receptors and various downstream signaling cascades
Did newborn Earth harbor life?
sea-maid submitted, created time 6 months 5 days (space.newscientist.com)
Life on Earth might have emerged about 750 million years earlier than previously thought, new research suggests.
Building the Tree of Life, Genome by Genome
sea-maid submitted, created time 6 months 6 days (www.sciencemag.org)
Phylogenetic studies have gone 'omic. Whereas researchers used to be satisfied comparing one gene, or a few, to sort out the branching of the tree of life, the push now among those building phylogenies is to consider whole genomes--at the very least, dozens of genes and thousands of DNA bases--in establishing kinships among flora and fauna. In this way, evolutionary biology is joining the bandwagon of data-intensive studies pioneered by genomics
Mechanism and function of humor identified by new evolutionary theory
sea-maid submitted, created time 6 months 1 week (esciencenews.com)
A new publication answers centuries' old questions regarding the mechanism and function of humour, identifying the reason humour is common to all human societies, its fundamental role in the evolution of homo sapiens and its continuing importance in the cognitive...
Dual Functions of the KNOTTED1 Homeodomain
jerry submitted, created time 6 months 3 weeks (stke.sciencemag.org)
This research found KNOTTED1 Homeodomain's dual functions. They are sequence-specific DNA binding and regulation of cell-to-cell transport
Spotlight on stem cell tracking
sea-maid submitted, created time 6 months 3 weeks (www.nature.com)
Making and employing stem cells is hard enough, but observing them is a whole other pack of trouble. This interview with cell imaging guru Timm Schroeder highlights how tough it can be to highlight stem cells in action. In particular, Schroeder talks of the applications of continuous observation. As it turns out, one of the biggest problems is keeping the specimen from moving.
Google launches free patient records
sea-maid submitted, created time 7 months 5 days (www.bmj.com)
The search engine giant has launched Google Health, a free service for patients offering a personal electronic medical record, but the move has prompted fears over the security of health information stored in this way.
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