96 Articles with the topic: Cardiovascular Disorders
Beating heart tissue produced in laboratories
sea-maid submitted, created time 6 months 3 weeks (www.nature.com)
An international team of researchers has used stem cells to create heart tissue, complete with beat. By treating embryonic stem cells with growth factors, they coaxed them into becoming cardiovascular progenitor cells, which then developed into cardiomyocytes, vascular smooth muscle cells, and endothelial cells, which together form blood vessels. When injected into the hearts of mice with induced heart disease, they improve heart function.
What this discovery does not include is fibroblasts, the cells that form the framework of the heart. 
What is the mechanisms of work stress and coronary heart disease?
kavin submitted, created time 6 months 4 weeks (eurheartj.oxfordjournals.org)
As known, in mordern times, people are suffering more and more work stress, which would hurt our heart, But wether the inevitability exsist between them is not known. Recently, a new study suggested work stress may be an important determinant of CHD among working-age populations, which is mediated through indirect effects on health behaviours and direct effects on neuroendocrine stress pathways.
Embryonic stem cells coaxed into key heart cells
sumsung submitted, created time 6 months 3 weeks (www.sciam.com)
Scientists say they have coaxed human embryonic stem cells into becoming three of the major cell types in the human heart, and they improved cardiac function when transplanted into mice. The findings, published in the journal Nature on Wednesday, showed that scientists can efficiently make different kinds of human heart cells for use in basic and clinical research. The researchers said that in the short term, they could be used to test how heart cells respond to different drugs
Adverse Cardiovascular Effects of Acute Salt Loading in Young Normotensive Individuals.
kavin submitted, created time 6 months 1 week (www.ncbi.nlm.nih.gov)
In the paper, the researchers explored the effects of salt loading in young normotensives on vascular endothelial function, echocardiographic left ventricular diastolic function, and electrocardiographic QT dispersion. Sixteen healthy normotensive male volunteers were randomized in a double-blind crossover fashion to 5-day treatment periods with either placebo or salt tablets (200 mmol/d of sodium) separated by a 2-week washout period
Intracardiac septation requires hedgehog-dependent cellular contributions
kavin submitted, created time 6 months 1 week (www.ncbi.nlm.nih.gov)
The researchers use a genetic marker and novel magnetic resonance microscopy techniques to demonstrate the origins of the dorsal mesenchymal protrusion in the dorsal mesocardium, and its substantial contribution to atrioventricular septation. They demonstrate that Shh signaling is required within the dorsal mesocardium for its contribution to the atria. Failure of this addition results in severe AVSD. These studies demonstrate that AVSD can result from a primary defect in dorsal mesocardium, providing a new paradigm for the understanding of human AVSD.
Should healthy people take statins too?
sea-maid submitted, created time 4 days 16 hours (www.nature.com)
The results of a study examining whether a potent cholesterol-lowering drug decreases the risk of heart disease are out. Rosuvastatin was given to 17,802 seemingly healthy people, and their chance of developing heart problems plummeted. The results, published in the New England Journal of Medicine, have revealed a number of questions about how to prevent heart attacks. Is exercise and a low-fat diet enough, or should large swathes of the population be prescribed preventative medication? Nature News gets to the heart of the matter.
Prescribed pot users face transplant hurdles
kavin submitted, created time 6 months 3 weeks (www.msnbc.msn.com)
Should using marijuana be held against a patient in need of transplant? About this question, there are several different views. And people tend to advise that there needs to be some kind of national eligibility criteria. Because the patients are trusting their physician to do the right thing. The physician prescribes marijuana, they take the marijuana, and they are shocked that this is now the end result. And no one tracks how many patients are denied transplants over medical marijuana use.
Non-peptide arginine-vasopressin antagonists: the vaptans
kavin submitted, created time 6 months 6 days (www.ncbi.nlm.nih.gov)
Arginine-vasopressin is a hormone that plays an important part in circulatory and water homoeostasis. These drugs are all effective in the treatment of euvolaemic and hypervolaemic hyponatraemia. Conivaptan is a V1a/V2 non-selective vasopressin-receptor antagonist that has been approved by the US Food and Drug Administration as an intravenous infusion for the inhospital treatment of euvolemic or hypervolemic hyponatremia.
Statins Lower Blood Marker for Prostate Cancer
piggy submitted, created time 2 weeks 5 days (www.healthday.com)
THURSDAY, Oct. 30 (HealthDay News) -- A new study shows that men who take cholesterol-lowering drugs called statins have lower blood levels of prostate-specific antigen (PSA), a biomarker for prostate cancer risk.
That drop in PSA levels doesn't necessarily mean the drugs protect against disease, however, researchers say.
But it's possible that statins may offer some protection against the disease, said Dr. Robert Hamilton, one author of the report in the Oct. 28 issue of the Journal of the National Cancer Institute
Flu Shots May Cut Risk of Blood Clots Forming in Veins
piggy submitted, created time 1 week 3 days (www.sciencedaily.com)
Flu shots may reduce the risk of blood clots forming in veins by 26 percent, according to research presented at the American Heart Association’s Scientific Sessions 2008.
“Our study suggests for the first time that vaccination against influenza may reduce the risk of venous thrombotic embolism (VTE),” said Joseph Emmerich, M.D., Ph.D., lead author of the study and professor of vascular medicine at the University Paris Descartes and head of the INSERM Lab 765, which investigates thrombosis. “This protective effect was more pronounced before the age of fifty-two years
New test to identify heart failure in emergency medicine found superior to current standards
piggy submitted, created time 1 week 2 days (www.reuters.com)
A new blood test to identify heart failure patients in most dire need of treatment when they turn up at an emergency room complaining of shortness of breath proved better than current tests, according to results of a study unveiled on Tuesday.
The pivotal trial of the test developed by privately held German company Brahms AG succeeded in its goal of demonstrating superiority over tests considered the current gold standard.
"I think that this is clearly significantly better than what we have now," Dr. W
Pollution Boosts Risk of Blood Clots As Well
sea-maid submitted, created time 6 months 1 week (www.efluxmedia.com)
In our opinion, it has long been known that pollution has noxious repercussions on our health, but no study stated that it might raise the risk of deep vein thrombosis (DVT) until today. In this study,we can found that the pollution can boost risk of blood clots.
How to stop a new type of heart attack
sea-maid submitted, created time 3 months 4 hours (technology.newscientist.com)
PACEMAKERS are supposed to protect people from heart attacks. But to do that they have to provide digital as well as biological security.
Earlier this year, a team led by William Maisel at Harvard Medical School demonstrated how a commercial radio transmitter could be used to modify wireless communications from a pacemaker (New Scientist, 22 March, p 23). Doctors normally use these signals to monitor and adjust the implanted device, but a malicious hacker could reprogram the pacemaker to give its wearer damaging shocks, or run down its batteries
First red blood cells grown in the lab
sea-maid submitted, created time 3 months 3 hours (www.newscientist.com)
Blood donations may one day be a thing of the past thanks to the creation of the first functional red blood cells grown in the lab. The cells were grown from human embryonic stem cells (ESCs).
Genetic study undermines case for CRP as cause of vascular disease
piggy submitted, created time 3 weeks 1 day (www.theheart.org)
Copenhagen, Denmark- Is C-reactive protein (CRP) a promoter of cardiovascular disease or simply a marker of increased cardiovascular risk? Probably the latter, according to the latest study to address the question, in which four gene variants tied to sharply increased CRP levels were shown not to be associated with an elevated CV-event risk
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