43 Articles with the topic: Dermatology
kavin submitted, created time 3 weeks 3 hours (www.medscape.com)
Four commonly used moisturizers promoted skin cancers in mouse studies.
Mice are not men. But the unexpected finding suggests that these — and perhaps other products — may not be as safe as they're thought to be.
The moisturizers tested in the study were Dermabase, Dermovan (a wholesale-only product discontinued in 2006), Eucerin Original Moisturizing Cream, and Vanicream.
In a mouse model of sun-related skin cancer, frequent application of each product resulted in more skin tumors and faster tumor growth, says study leader Allan H 
Intermittent Tacrolimus Ointment Therapy Helps Prevent Relapse of Stabilized Atopic Dermatitis
kavin submitted, created time 2 months 5 days (www.medscape.com)
NEW YORK (Reuters Health) Jun 23 - In patients with stabilized atopic dermatitis, intermittent therapy with tacrolimus ointment was associated with significantly more flare-free days and longer time to first relapse compared with vehicle alone, according to a report in the June issue of the Journal of the American Academy of Dermatology.
Tacrolimus is a topical calcineurin inhibitor (TCI) and is manufactured in ointment form under the brand name Protopic by Astellas Pharma US Inc., which supported this multicenter study by U.S. researchers
The military AFIRMs regenerative medicine
Darkfrog submitted, created time 2 months 1 week (www.popsci.com)
As of this past March, thirty different research institutions have joined to become the Armed Forces Institute of Regenerative Medicine (AFIRM). With $250-million in funding, they plan to expand ideas like the "pixie dust" limb regrowth method that was mentioned on DiscoveR8 a few months back. Most interestingly, there are plans for a handheld spritzer that would spray keratinocytes directly onto burns and wounds.
I followed the links to this one. A few blogs wrote articles based on this one, but focusing on just the burn sprayer, which they've nicknamed the "stem cell gun
Melanoma Cured 100% through Blood Cell Therapy
kavin submitted, created time 2 months 2 weeks (www.efluxmedia.com)
The results of a new study conducted by a researcher team at the Fred Hutchinson Cancer Research Center in Seattle, give hope for those suffering from melanoma, one of the rarer types of skin cancer but the one which causes the majority of skin cancer related deaths.
Researchers who took part in the study used a patient's cloned T cells (helper cells) to put an advanced cancer into complete remission. Nine patients took part in the experimental melanoma treatment program.
The researchers were very surprised after they treated a 52-year-old man from Oregon of his Stage 4 melanoma
Breaking out new ideas on molting
kavin submitted, created time 2 months 2 weeks (www.jcb.org)
Alison Frand believes that understanding the molting process of the nematode worm, C. elegans, might provide new insights into diseases affecting humans. Some of the potential medical benefits lie in the similarities between the worms' exoskeleton and our own skin and connective tissues, while other benefits might lie in the unique aspects of worm molting. Alison Frand is using RNAi, GFP-PEST, and other state-of-the-art tools to study molting in worms.
Stem cell treatment leaves boy with recessive epidermolysis bullosa improving daily
Darkfrog submitted, created time 2 months 4 weeks (www.latimes.com)
Two-year-old Nate Liao is eating solid food, playing with his sibs and generally running around and getting into things. The reason? His body has started producing collagen VII, the material that anchor's a person's skin to the rest of his body. Before he was treated, the least contact could cause bruising and blisters. Eating anything non-liquid could tear the lining of his esophagus.
Some of Nate's doctors are suggesting that epidermolysis bullosa be taken "off the incurable list." Little Nate was given a mixture of bone marrow and cord blood stem cells
Vincent submitted, created time 5 months 3 days (content.nejm.org)
Atopic dermatitis, or eczema, is a common skin disease that is often associated with other atopic disorders, such as allergic rhinitis and asthma 1. The clinical manifestations of atopic dermatitis vary with age; three stages can often be identified. In infancy, the first eczematous lesions usually emerge on the cheeks and the scalp. Scratching, which frequently starts a few weeks later, causes crusted erosions. During childhood, lesions involve flexures, the nape, and the dorsal aspects of the limbs. In adolescence and adulthood, lichenified plaques affect the flexures, head, and neck
Sounding the Alarm: Multiple Functions of Host Defense Peptides
davidd submitted, created time 7 months 4 days (www.nature.com)
The capacity of the skin and other organs to resist infection depends on the innate production of molecules known as antimicrobial peptides. Emerging evidence suggests that some of these peptides are important to immune defense by acting not only as natural antibiotics but also as cell-signaling molecules.
Research suggests mechanism for acne drug’s link to depression
sally79 submitted, created time 8 months 2 weeks (www.scienceabode.com)
the article reveals interesting information on a acne drug causing depression.
TB-scarred Homo erectus skull found in Turkey
Darkfrog submitted, created time 8 months 2 weeks (www3.interscience.wiley.com)
The article discusses the way in which TB affected migrating populations. According to the article, examination of this skull supports the idea that as dark-skinned hominids moved into areas where the sun was less intense, they found themselves deficient in vitamin D, which affected their bones and immune systems.
It also got a writeup in the New York Times.
http://www.nytimes.com/2007/12/18/science/18skul.html?ref=science
Face transplant doctors recount recovery
annatto submitted, created time 8 months 3 weeks (www.earthtimes.org)
BOSTON, Dec. 14 The medical team that performed the first face transplant says their French patient is satisfied with the results of the 2005 operation.
Good News: Stem Cells Overpower Muscle Disease
Eric wu submitted, created time 8 months 3 weeks (sciencenow.sciencemag.org)
The recent breakthrough of skin cells reprogrammed to behave like embryonic stem cells has stolen the spotlight (ScienceNOW, 6 December), but adult stem cells are proving that they have advantages of their own. In the 13 December issue of Cell Stem Cell, researchers report using stem cells from patients afflicted with a form of muscular dystrophy to correct the disorder in mice. The results suggest that this strategy could one day treat muscular dystrophy in humans as well as other genetic disorders.
Skin cream tackles skin cancers in mice
jane2007 submitted, created time 9 months 3 days (www.nature.com)
A skin cream that can hyperactivate the body's natural DNA repair mechanisms has been shown to protect mice from skin cancer, and to reduce the growth of cancers already present. If the compound does the same for humans, it could one day be added to sunscreen as a cancer-fighting ingredient.
It's very interesting, isn't it?
When Surgery Succeeds, But Healing Fails
Eric wu submitted, created time 9 months 1 week (www.time.com)
A surgeon uses a scalpel to incise the skin, beginning an exploratory celiotomy....... But when a wound doesn't heal, what then? Professor of Orthopedic Surgery adds another d to "FRIEND."
Clinical decision modeling system
biomedguru submitted, created time 10 months 4 days (www.biomedcentral.com)
This paper describes the world's first software designed specifically to facilitate integrative translational research. Researchers using the software will be able to plan effective integrative clinical trials that examine the utility of specific clinical workflows that integrate biomarkers, imaging, clinical and demographic data.
The software is available online here:
http://bioinformatics.pitt.edu/software/cdms/
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