83 Articles with the topic: Gastroenterology & Hepatology
New Pathway for Malaria Infection Discovered
sea-maid submitted, created time 3 weeks 23 hours (www.sciencedaily.com)
Cenix BioScience GmbH, a leading specialist in advanced RNA interference (RNAi)-based research services, Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), a leading RNAi therapeutics company, and the Lisbon-based biomedical research centre Instituto de Medicina Molecular (IMM), have announced the publication of their collaborative study in Cell Host & Microbe, describing the discovery and in vivo validation of scavenger receptor BI (SR-BI), a major regulator of cholesterol uptake by the liver, as a critical host factor for malaria infection. 
Study shows cost savings behind bariatric surgery
jerry submitted, created time 3 weeks 5 days (money.cnn.com)
Insurance companies do usually cover the costs of bariatric surgery, they would start now: A new study shows that, among morbidly obese patients, having a stomach stapling or an intestinal modification causes them to shed insurance claims as well as pounds.
The study looked at the insurance claims of 7200 morbidly obese patients, half of whom had had the surgery and half of whom had not
sea-maid submitted, created time 1 month 3 weeks (sciencenow.sciencemag.org)
Humans have been trying to outrun old age for millennia, and new research might give us a step on the Grim Reaper. Scientists have prevented age-related liver decline in mice by restoring a key protein that helps the organ trash used proteins. It's not exactly the fountain of youth, but the findings could shed further light on the biological mechanisms of aging.....
Five Factors Predict Success in Gastric Banding Procedure
kavin submitted, created time 3 months 5 days (www.medscape.com)
June 19, 2008 (Washington, DC) — A nationwide survey in France has found five factors that are significantly associated with successful weight loss after gastric banding. The study was part of a survey of medical and surgical practices conducted by the French National Medical Insurance Service and presented here at the American Society for Metabolic & Bariatric Surgery 25th Annual Meeting. "Success" was defined as the loss of more than 50% of excess body weight.
The advent of capsule endoscopy--a not-so-futuristic approach to obscure gastrointestinal bleeding
kavin submitted, created time 3 months 1 week (www.ncbi.nlm.nih.gov)
Capsule endoscopy is a new, wireless, endoscopic examination of the small intestine. To date, two small clinical trials have been reported utilizing capsule endoscopy in patients with obscure gastrointestinal bleeding, and have shown its superiority to push enteroscopy in diagnosing the cause of blood loss. No outcome studies have been reported. This paper proposes a change in practice guidelines for obscure bleeding
Higher coffee consumption associated with lower liver cancer risk
kavin submitted, created time 3 months 1 week (esciencenews.com)
A new large, prospective population-based study confirms an inverse relationship between coffee consumption and liver cancer risk. The study also found that higher levels of gamma-glutamyltransferase (GGT) in the blood were associated with an increased risk of developing the disease. These findings are published in the July issue of Hepatology, a journal published by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases (AASLD). The article and an accompanying editorial are also available online at Wiley Interscience (www.interscience.wiley.com)
Study finds safer, more efficient medication for hepatitis B treatment
kavin submitted, created time 3 months 1 week (esciencenews.com)
Patients with hepatitis B who did not respond to lamivudine therapy had a better virological response after switching to entecavir for a year. Continuing the drug for an additional year led to even more clinical improvement without significant side effects, according to a new study in the July issue of Hepatology, a journal published by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases (AASLD). The article is also available online at Wiley Interscience (www.interscience.wiley.com). Chronic hepatitis B is the tenth leading cause of death worldwide
New Weapon for Attacking Tumor Invasion and Metastasis
kavin submitted, created time 3 months 1 week (www.mphtimes.com)
A team led by Dr. Ji-Kun Li has determined that AMD3100, originally developed in acquired immune deficiency syndrome treatment, could markedly inhibit spreading of colorectal cancer cells by blocking a new pair of ligands and its unique receptor. This effect differs from the usual inhibition by a conventional chemotherapic agent that is more specific to cancer cells with high metastatic potential.
In vitro, AMD3100 has shown a significantly inhibitory effect on invasion and migration in colorectal cancer cell line. This effect can be further enhanced at higher concentration
Bacteria can learn to anticipate changes in their environments
Sue Wu submitted, created time 4 months 4 weeks (www.nature.com)
The simple life of bacteria is a little less simple than you might have thought. New research shows that colonies of Escherichia coli can demonstrate a form of learning.
Stomach hormone turns hungry people into junkies
sea-maid submitted, created time 5 months 4 hours (www.newscientist.com)
In this paper ,the researchers point out that stomach hormone turns hungry people into junkies.When volunteers received a dose of a natural hunger-inducing hormone called ghrelin, their brains responded to pictures of food in the same way that addicted people's brains do to cigarettes or drugs, says Alain Dagher, a neurologist at McGill University in Montreal, Canada, who led the study.
And the study also tell us that hormone has its stimulant effects and Memory improvement,mood changes.
Environmental and genetic modifiers of the progression to fibrosis and cirrhosis in hemochromatosis
sea-maid submitted, created time 5 months 1 week (bloodjournal.hematologylibrary.org)
Hemochromatosis is a disease related to a relatively common and easily identifiable genetic defect, but the extent of clinical expression is variable and to a large extent remains unexplained. But this review explores recent developments in knowledge of environmental and genetic modifiers of this process.
Metabolism indeed varies between populations
Sue Wu submitted, created time 5 months 2 weeks (www.nature.com)
Thousands of frozen urine samples have yielded new information about the diversity of human metabolism across the globe — about who eats what, and how their unique internal microorganisms handle the input.
Sue Wu submitted, created time 6 months 3 weeks (www.sciencenews.org)
Hydrogen sulfide deserves its bad reputation. It's famous for filling the air of high school chemistry labs with the smell of rotten eggs. One strong whiff of the noxious gas can knock you to the ground. Too much can kill you. However, recent discoveries show that in the right proportions, H2S helps regulate several different bodily functions. In fact, we can't live without it.
Serum Levels of Apolipoprotein A-II as a Potential Marker for Cholangiocarcinoma
MedUnion submitted, created time 7 months 3 weeks (www.mupnet.com)
AIM: Cholangiocarcinoma (CC) is a devastating neoplasm usually hard to get diagnosed in the early stage due to the unfavorable anatomic location. The currently used tumor markers like CEA and CA 19-9 are not always helpful because of the unsatisfactory sensitivities and specificities. In this study, surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF-MS) was used to identify the potential biomarker for CC
Expression and Prognostic Significance of EpCAM
MedUnion submitted, created time 7 months 3 weeks (www.mupnet.com)
AIM: EpCAM (CD326) is a transmembrane glycoprotein on epithelial cells. To assess its expression, an increasing number of commercially available antibodies combined with multiple staining protocols with varying sensitivities and specificities are in use. There is no consensus about definition of positivity. Systematic and reliable comparison of results is therefore hampered. To maximise the reproducibility of the results, we investigated EpCAM expression on tissue microarrays
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