27 Articles with the topic: Gastroenterology & Hepatology
Stomach hormone turns hungry people into junkies
sea-maid submitted, created time 8 months 2 days (www.newscientist.com)
In this paper ,the researchers point out that stomach hormone turns hungry people into junkies.When volunteers received a dose of a natural hunger-inducing hormone called ghrelin, their brains responded to pictures of food in the same way that addicted people's brains do to cigarettes or drugs, says Alain Dagher, a neurologist at McGill University in Montreal, Canada, who led the study.
And the study also tell us that hormone has its stimulant effects and Memory improvement,mood changes. 
Stem Cells with Potential to Regenerate Injured Liver Tissue Identified
sea-maid submitted, created time 1 month 3 weeks (www.sciencedaily.com)
A novel protein marker has been found that identifies rare adult liver stem cells, whose ability to regenerate injured liver tissue has the potential for cell-replacement therapy. For the first time, researchers at the University of Pennsylvania School of Medicine led by Linda Greenbaum, MD, Assistant Professor of Medicine in the Division of Gastroenterology, have demonstrated that cells expressing the marker can differentiate into both liver cells and cells that line the bile duct.
This discovery could have serious implication for transplants and regenerative medicine
Environmental and genetic modifiers of the progression to fibrosis and cirrhosis in hemochromatosis
sea-maid submitted, created time 8 months 1 week (bloodjournal.hematologylibrary.org)
Hemochromatosis is a disease related to a relatively common and easily identifiable genetic defect, but the extent of clinical expression is variable and to a large extent remains unexplained. But this review explores recent developments in knowledge of environmental and genetic modifiers of this process.
Amish provide clues to genetics of heart disease
piggy submitted, created time 3 weeks 6 days (sciencenow.sciencemag.org)
Downing eight-hundred-calorie milkshakes is a great way to make the fat levels in your blood skyrocket. But a small proportion of Amish in Lancaster County, Pennsylvania, are not so easily affected, researchers have found. These lucky few harbor a genetic mutation that keeps their levels of fat particles called triglycerides in check and possibly protects them from heart disease. Although their particular mutation doesn't show up very often in the general population, the gene itself could play an important role in heart disease
New genetic markers for ulcerative colitis identified
piggy submitted, created time 3 days 21 hours (www.eurekalert.org)
An international team led by University of Pittsburgh School of Medicine researchers has identified genetic markers associated with risk for ulcerative colitis. The findings, which appear today as an advance online publication of the journal Nature Genetics, bring researchers closer to understanding the biological pathways involved in the disease and may lead to the development of new treatments that specifically target them.
Ulcerative colitis is a chronic, relapsing disorder that causes inflammation and ulceration in the inner lining of the rectum and large intestine
Bariatric surgery hangs up its scalpel
Darkfrog submitted, created time 2 months 2 weeks (www.nytimes.com)
In serious cases of obsity, patients sometimes opt for bariatric surgery--modifications to the stomach. This may include staples or cinchers, but the effect is that the stomach is shrunk so that the patient feels full after eating only a little. The surgical techniques involved have become more precise over the years, and many bariatric surgeries have been performed through only a tiny slit in the patient's abdominal wall
Antioxidants Offer Pain Relief in Patients with Chronic Pancreatitis
sea-maid submitted, created time 5 days 6 hours (www.docguide.com)
Antioxidant supplementation was found to be effective in relieving pain and reducing levels of oxidative stress in patients with chronic pancreatitis (CP), according to a study published in the January issue of the journal Gastroenterology.
Antibiotics Largest Cause of Drug-Induced Liver Damage
sea-maid submitted, created time 1 month 6 days (health.msn.com)
MONDAY, Dec. 1 (HealthDay News) -- Antibiotics are the single largest class of drugs that cause idiosyncratic drug-induced liver injury (DILI), researchers say.
The condition accounts for about thirteen percent of cases of acute liver failure in the United States and is the most common cause of death from acute liver failure.
DILI is caused by a wide range of prescription and nonprescription medications, nutritional supplements and herbal products
Extended Drug Therapy for Hepatitis Is Challenged
sea-maid submitted, created time 1 month 4 days (www.theledger.com)
Patients who do not initially respond to standard drug therapy for treatment of hepatitis C are unlikely to respond to long-term maintenance therapy as well, according to a new study.
Is bismuth a safe medicine for the treatment of peptic ulcer disease?
sea-maid submitted, created time 1 week 1 day (www.eurekalert.org)
Bismuth compounds have been used for centuries in medicine. The discovery of H. pylori in 1983 led to renewed interest in bismuth compounds, because these were found to successfully treat the infection in combination with antibiotics. However, in the 1970s bismuth salts, used at high doses for prolonged periods, were found to lead to neurotoxicity. However, there has been no summary of evidence for the toxicity of bismuth when used for short periods as part of H. pylori eradication therapy and some researchers think it might have applications in treating ulcers.
Sue Wu submitted, created time 9 months 4 weeks (www.sciencenews.org)
Hydrogen sulfide deserves its bad reputation. It's famous for filling the air of high school chemistry labs with the smell of rotten eggs. One strong whiff of the noxious gas can knock you to the ground. Too much can kill you. However, recent discoveries show that in the right proportions, H2S helps regulate several different bodily functions. In fact, we can't live without it.
sea-maid submitted, created time 4 months 4 weeks (sciencenow.sciencemag.org)
Humans have been trying to outrun old age for millennia, and new research might give us a step on the Grim Reaper. Scientists have prevented age-related liver decline in mice by restoring a key protein that helps the organ trash used proteins. It's not exactly the fountain of youth, but the findings could shed further light on the biological mechanisms of aging.....
New Pathway for Malaria Infection Discovered
sea-maid submitted, created time 3 months 3 weeks (www.sciencedaily.com)
Cenix BioScience GmbH, a leading specialist in advanced RNA interference (RNAi)-based research services, Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), a leading RNAi therapeutics company, and the Lisbon-based biomedical research centre Instituto de Medicina Molecular (IMM), have announced the publication of their collaborative study in Cell Host & Microbe, describing the discovery and in vivo validation of scavenger receptor BI (SR-BI), a major regulator of cholesterol uptake by the liver, as a critical host factor for malaria infection.
Metabolism indeed varies between populations
Sue Wu submitted, created time 8 months 2 weeks (www.nature.com)
Thousands of frozen urine samples have yielded new information about the diversity of human metabolism across the globe — about who eats what, and how their unique internal microorganisms handle the input.
New Weapon for Attacking Tumor Invasion and Metastasis
kavin submitted, created time 6 months 2 weeks (www.mphtimes.com)
A team led by Dr. Ji-Kun Li has determined that AMD3100, originally developed in acquired immune deficiency syndrome treatment, could markedly inhibit spreading of colorectal cancer cells by blocking a new pair of ligands and its unique receptor. This effect differs from the usual inhibition by a conventional chemotherapic agent that is more specific to cancer cells with high metastatic potential.
In vitro, AMD3100 has shown a significantly inhibitory effect on invasion and migration in colorectal cancer cell line. This effect can be further enhanced at higher concentration
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