565 Articles with the topic: Immunology
Chemical from Medicinal Plants May Be Used to Fight HIV
piggy submitted, created time 4 days 5 hours (www.sciencedaily.com)
Like other kinds of cells, immune cells lose the ability to divide as they age because a part of their chromosomes known as a telomere becomes progressively shorter with cell division. As a result, the cell changes in many ways, and its disease fighting ability is compromised.
But a new UCLA AIDS Institute study has found that a chemical from the Astragalus root, frequently used in Chinese herbal therapy, can prevent or slow this progressive telomere shortening, which could make it a key weapon in the fight against HIV 
New Therapy Could Transform Arthritis Treatment
sea-maid submitted, created time 6 days 5 hours (health.msn.com)
New understanding about how to control autoimmune responses offers promise in efforts to develop treatments for rheumatoid arthritis (RA), British researchers say.
How Eating Red Meat Can Spur Cancer Progression: New Mechanism Identified
piggy submitted, created time 1 week 4 hours (www.sciencedaily.com)
Researchers at the University of California, San Diego School of Medicine, led by Ajit Varki, M.D., have shown a new mechanism for how human consumption of red meat and milk products could contribute to the increased risk of cancerous tumors.
Their findings, which suggest that inflammation resulting from a molecule introduced through consumption of these foods could promote tumor growth, are published online this week in advance of print publication in the Proceedings of the National Academy of Sciences (PNAS)
Rheumatoid Arthritis Breakthrough
piggy submitted, created time 1 week 1 day (www.sciencedaily.com)
Rheumatoid arthritis is a painful, inflammatory type of arthritis that occurs when the body's immune system attacks itself. A new article reports a breakthrough in the understanding of how autoimmune responses can be controlled, offering a promising new strategy for therapy development for rheumatoid arthritis.
Normally, immune cells develop to recognise foreign material – antigens; including bacteria - so that they can activate a response against them. Immune cells that would respond to 'self' and therefore attack the body's own cells are usually destroyed during development
How the Body Determines Optimal Amount of Germ-Fighting B Cells
piggy submitted, created time 1 week 4 days (www.sciencedaily.com)
Researchers at the University of Pennsylvania School of Medicine can now explain how the body determines whether there are enough mature B-cells in the blood stream at any one time. These are the cells that produce antibodies against germs to fight infections.
“There is a steady state number of B cells that is considered normal for humans,” says senior author Michael P. Cancro, PhD, Professor of Pathology and Laboratory Medicine
New Role for Critical DNA Repair Molecule in Immune System
piggy submitted, created time 1 week 4 days (www.sciencedaily.com)
The human immune system is a brilliantly adaptable weapon against foreign invaders. But it all depends on the work of specialized cells called lymphocytes that have made a risky evolutionary gambit to mutate their own DNA. New research published in Nature shows for the first time that a molecule devoted to DNA repair plays a broader role in this genetic reshuffling — called recombination — than scientists had thought
Key Gene May Be Crucial to Production of Thymus and Disease-Fighting T-cells
sea-maid submitted, created time 1 week 5 days (gopast.net)
This research provides the first evidence that a key gene may be crucial to maintaining the production of the thymus and its disease-fighting T-cells after an animal’s birth.
HIV vaccine failure explained?
sea-maid submitted, created time 2 weeks 1 day (www.nature.com)
Researchers have suggested that an experimental vaccine against AIDS might have failed in part because it made some people's immune cells more vulnerable to HIV infection.
Scientists turbo-charge immune cells to fight cancer
piggy submitted, created time 2 weeks 3 days (news.yahoo.com)
Scientists in the United States have created super-charged immune cells that helped beat back cancer tumors in half of a small group of patients tested, according to a study released Sunday.
Adding an artificial receptor to T-lymphocyte immune cells boosted their ability to fight a deadly form of cancer called neuroblastoma, the researchers reported.
Neuroblastoma attacks the nervous system. While fairly rare, it accounts for seven percent of all childhood cancers, and fifteen percent of non-adult cancer deaths
CD20 blockers eye crowded rheumatology market
sea-maid submitted, created time 1 month 1 day (www.nature.com)
When trial results for a novel cancer drug were trumpeted in July, the rheumatology field felt the ripples. The drug is ofatumumab, a monoclonal antibody (mAb) targeting the CD20 molecule on B lymphocytes. Its makers, London-based GlaxoSmithKline (GSK) and Genmab of Copenhagen, announced that the mAb had met its primary and secondary endpoints in chronic lymphocytic leukemia (CLL)
Can Mesenchymal Stem Cells Induce Tolerance to Cotransplanted Human Embryonic Stem Cells?
jerry submitted, created time 1 month 2 days (www.nature.com)
Mesenchymal stem cells (MSCs) are reported to be immune privileged. We assessed whether their transplantation (Tx) could create a suppressive microenvironment mitigating rejection of coinjected human embryonic stem cells (hESCs)...
Discovery of natural compounds that could slow blood vessel growth
sea-maid submitted, created time 1 month 2 weeks (esciencenews.com)
Using a whole-genome approach, researchers have found more than one hundred human protein compounds that can slow blood vessel growth. This could lead to treatments against diseases that depend on the growth of new blood vessels, including cancer, macular degeneration and rheumatoid arthritis.
Monoclonal antibodies come of age, and passive immunity treatments come around
sea-maid submitted, created time 1 month 4 weeks (www.nature.com)
Monoclonal antibodies, antibodies that are made from a single cell line and that bind to a specific part of a specific antigen, are much more precise than polyclonal antibodies, but they are more expensive and difficult to make. However, a new system of isolating antibodies from human patients has been used to create a library of immune proteins. So far, things seem to be going well. This could open the door for what researchers are calling "passive immunity
Maternal flu shots protect newborns: U.S. study
jerry submitted, created time 2 months 3 days (www.reuters.com)
Flu shots given to pregnant women a month or more before delivery will prevent most cases of influenza during the first six months of their babies' lives, researchers said.
Link Between Vitamin D And Multiple Sclerosis
kavin submitted, created time 2 months 2 weeks (www.medicalnewstoday.com)
Vitamin D, the principal regulator of calcium in the body, may prevent the production of malignant cells such as breast and prostate cancer cells and protect against specific autoimmune disorders including multiple sclerosis (MS) according to an article by Sylvia Christakos, PhD, of the UMDNJ-New Jersey Medical School.
In the article, Christakos reports that research shows that the incidence of MS decreases as the amount of vitamin D available to the body increases, either through sunlight exposure or diet
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