944 Articles with the topic: Oncology
Broccoli May Lower Lung Cancer Risk in Smokers
piggy submitted, created time 2 days 24 minutes (www.sciencedaily.com)
The cancer preventive properties of broccoli and other cruciferous vegetables appear to work specifically in smokers, according to data presented at the American Association for Cancer Research's Seventh Annual International Conference on Frontiers in Cancer Prevention Research.
Cruciferous vegetables have been shown to be protective in numerous studies, but this is the first comprehensive study that showed a protective benefit in smokers, specifically in former smokers, according to lead author Li Tang, Ph.D., a post-doctoral fellow at Roswell Park Cancer Institute 
Tumor Secrets Written in Blood
piggy submitted, created time 2 days 21 hours (sciencenow.sciencemag.org)
Doctors may soon be able to use blood tests rather than invasive biopsies to figure out what type of brain tumors their patients have. The findings, which come thanks to new insights about how tumor cells communicate with their environment, may also bring physicians closer to the goal of more personalized medicine.
Cells are chatty, constantly exchanging proteins or electrical signals with their neighbors. For example, tumor cells can signal nearby blood vessels to grow in their direction, thereby facilitating tumor growth
Calcium May Only Protect Against Colorectal Cancer in Presence of Magnesium
sea-maid submitted, created time 2 days 21 hours (www.sciencedaily.com)
High magnesium intake has been associated with low risk of colorectal cancer. Americans have similar average magnesium intake as East Asian populations. If that were all that were involved, observers might expect both groups to have similar risk for colorectal cancer
Men who take aspirin have significantly lower PSA levels
sea-maid submitted, created time 3 days 20 hours (www.genengnews.com)
The use of aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) is significantly associated with lower PSA levels, especially among men with prostate cancer, say researchers at Vanderbilt University.
DNA: Too Much--or Too Little--Can Be a Bad Thing
piggy submitted, created time 4 days 11 hours (sciencenow.sciencemag.org)
There's more variety to DNA than you might think: Deletions or additions of genetic material between individuals, called copy number variations (CNVs), are a common source of genetic diversity. Now, preliminary work reported here today at the American Society of Human Genetics meeting suggests that men who have more CNVs than average may be more likely to sire children with the eye cancer retinoblastoma
Study yields clues to why some tumors spread
sea-maid submitted, created time 5 days 22 hours (www.sciam.com)
A small fragment of genetic material may mean the difference between an easily treated local tumor and an aggressive cancer that spreads throughout the body, U.S. researchers said on Thursday.
How Eating Red Meat Can Spur Cancer Progression: New Mechanism Identified
piggy submitted, created time 6 days 21 hours (www.sciencedaily.com)
Researchers at the University of California, San Diego School of Medicine, led by Ajit Varki, M.D., have shown a new mechanism for how human consumption of red meat and milk products could contribute to the increased risk of cancerous tumors.
Their findings, which suggest that inflammation resulting from a molecule introduced through consumption of these foods could promote tumor growth, are published online this week in advance of print publication in the Proceedings of the National Academy of Sciences (PNAS)
Starving tumors of blood vessels may not be the way to go
piggy submitted, created time 1 week 19 hours (www.sciencedaily.com)
Dense networks of blood vessels thought to spur cancer’s growth could actually hinder rather than promote tumor progression, according to a new study at the University of California, San Diego.
The findings partly explain why drugs designed to treat cancer by strangling its blood supply have been disappointing when used alone and why those treatments are more effective when combined with traditional chemotherapy
Industry shifts focus to immunology and cancer
sea-maid submitted, created time 1 week 3 days (www.nature.com)
Economic factors, including competition from generic drugs, is hitting even the big pharmaceutical companies hard, reports Nature. In 2010, Pfizer's Lipitor enters the public domain. For these reasons, the larger companies are narrowing the focus of their research, hitting fewer diseases. They're also working on fewer primary care drugs and more drugs that would be prescribed by specialists, such as cancer drugs.
"When Wyeth Pharmaceuticals announced last week that it would cut some of its research and development (R&D) programs in women's health, the decision seemed counterintuitive
Researchers Discover Achilles' Heel in Pancreatic Cancer
sea-maid submitted, created time 1 week 5 days (gopast.net)
UC Davis Cancer Center researchers have discovered a metabolic deficiency in pancreatic cancer cells that can be used to slow the progress of the deadliest of all cancers.
Gene Variations Alter Risk of Esophageal Cancer
piggy submitted, created time 2 weeks 21 hours (www.sciencedaily.com)
ScienceDaily (Nov. 6, 2008) — Variations in a common gene pathway may affect esophageal cancer risk, a dangerous and rapidly increasing type of cancer, according to research by scientists at The University of Texas M. D. Anderson Cancer Center.
Results of the study, which is the first to look at the association between variations in genes related to microRNAs (miRNAs) and esophageal cancer, are published in the November issue of Cancer Prevention Research, a journal of the American Association of Cancer Research.
Scientists turbo-charge immune cells to fight cancer
piggy submitted, created time 2 weeks 2 days (news.yahoo.com)
Scientists in the United States have created super-charged immune cells that helped beat back cancer tumors in half of a small group of patients tested, according to a study released Sunday.
Adding an artificial receptor to T-lymphocyte immune cells boosted their ability to fight a deadly form of cancer called neuroblastoma, the researchers reported.
Neuroblastoma attacks the nervous system. While fairly rare, it accounts for seven percent of all childhood cancers, and fifteen percent of non-adult cancer deaths
Cytokines and their relationship to the symptoms and outcome of cancer
sea-maid submitted, created time 2 weeks 2 days (www.nature.com)
Tumors contain immune cells and a network of pro- and anti-inflammatory cytokines, which collaborate in the development and progression of cancer. Cytokine profiles might prove to be prognostic. The systemic effects of pro-inflammatory cytokines are associated with fatigue, depression and cognitive impairment, and can affect quality of life before, during and after treatment. In people with advanced cancer, pro-inflammatory cytokines are additionally associated with anorexia and cachexia, pain, toxicity of treatment and resistance to treatment
sea-maid submitted, created time 2 weeks 4 days (www.nature.com)
New studies have affirmed the complexity of genetic changes in solid tumors, but also revealed commonalities in the associated pathways, suggesting that a pathway-oriented perspective could aid cancer drug discovery and therapy.
Statins Lower Blood Marker for Prostate Cancer
piggy submitted, created time 2 weeks 5 days (www.healthday.com)
THURSDAY, Oct. 30 (HealthDay News) -- A new study shows that men who take cholesterol-lowering drugs called statins have lower blood levels of prostate-specific antigen (PSA), a biomarker for prostate cancer risk.
That drop in PSA levels doesn't necessarily mean the drugs protect against disease, however, researchers say.
But it's possible that statins may offer some protection against the disease, said Dr. Robert Hamilton, one author of the report in the Oct. 28 issue of the Journal of the National Cancer Institute
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