231 Articles with the topic: Oncology
The findings about How Stomach Tumors Form
sea-maid submitted, created time 6 months 3 weeks (www.wlns.com)
Stomach cancer is the second most common cause of cancer-related deaths worldwide. Many people are rightly concerned about this disease. In this article, the study shows us how stomach tumors form. Stomach cancer has been shown, previously, to be correlated with chronic inflammation. 
Cell: A key pathway of acute lung injury-Oxidative
kavin submitted, created time 6 months 4 weeks (www.cell.com)
Multiple lung pathogens such as SARS cause high lethality due to acute respiratory distress syndrome. The researchers, through experiments in mice, indentify oxidative stress and innate immunity as key lung injury pathways that control the severity of ALI.
Protein test predicts invasive breast cancer
sea-maid submitted, created time 6 months 3 weeks (www.newscientist.com)
Cancer is one of the world’s biggest killers. Only have we known more about the principal of the breast cancer, we can create more useful methods to prevent the diseaes. Now, a team at the University of California has developed a test that can determine whether or not a woman's tumor will turn invasive--and whether or not she should go through with surgery.
kavin submitted, created time 5 months 3 days (www.businesswire.com)
TM601 is a novel synthetic peptide targeting both primary tumors and metastases and it will give us some hope in the battle against cancer. Derived from scorpion venom, TM601 binds to receptors on cancer cells but leaves healthy cells alone. When TM601 is tagged with radioactive iodine, it can deliver a tiny, targeted dose of radiation to cancer cells, killing them while leaving healthy tissue unharmed.
The potential of TM601 is so high that the FDA has granted its iodine-labeled form orphan drug status for patients with malignant gliomas
Cancer stem cells in solid tumors: accumulating evidence and unresolved questions
sea-maid submitted, created time 1 month 1 day (www.nature.com)
Solid tumors are an enormous cancer burden and a major therapeutic challenge. The cancer stem cell (CSC) hypothesis provides an attractive cellular mechanism to account for the therapeutic refractoriness and dormant behavior exhibited by many of these tumors. There is increasing evidence that diverse solid tumors are hierarchically organized and sustained by a distinct subpopulation of CSCs. Direct evidence for the CSC hypothesis has recently emerged from mouse models of epithelial tumorigenesis, although alternative models of heterogeneity also seem to apply
Scientists turbo-charge immune cells to fight cancer
piggy submitted, created time 2 weeks 2 days (news.yahoo.com)
Scientists in the United States have created super-charged immune cells that helped beat back cancer tumors in half of a small group of patients tested, according to a study released Sunday.
Adding an artificial receptor to T-lymphocyte immune cells boosted their ability to fight a deadly form of cancer called neuroblastoma, the researchers reported.
Neuroblastoma attacks the nervous system. While fairly rare, it accounts for seven percent of all childhood cancers, and fifteen percent of non-adult cancer deaths
Broccoli May Lower Lung Cancer Risk in Smokers
piggy submitted, created time 1 day 23 hours (www.sciencedaily.com)
The cancer preventive properties of broccoli and other cruciferous vegetables appear to work specifically in smokers, according to data presented at the American Association for Cancer Research's Seventh Annual International Conference on Frontiers in Cancer Prevention Research.
Cruciferous vegetables have been shown to be protective in numerous studies, but this is the first comprehensive study that showed a protective benefit in smokers, specifically in former smokers, according to lead author Li Tang, Ph.D., a post-doctoral fellow at Roswell Park Cancer Institute
Tumor cells share oncogenic receptors
sea-maid submitted, created time 6 months 1 week (www.jcb.org)
Mutant receptors made in one tumor cell can be passed to tumor cells lacking them.
In this study, the authors found that glioma cells expressing EGFRvIII transferred this errant receptor to nonexpressing cells via microvesicles--small plasma membrane buds. The microvesicles were produced in abundance by the mutant expressing cells and were widely taken up by receptor-negative cells
Tumorigenesis: Keeping a watchful eye
sea-maid submitted, created time 3 weeks 5 days (www.nature.com)
Disruptions in the delicate balance between keratinocyte proliferation and differentiation can contribute towards the development of squamous cell carcinoma (SCC) of the skin — a common human malignancy. It has been proposed that innate surveillants, molecules that promote terminal keratinocyte differentiation, exist in the skin to prevent carcinogenesis, but the conclusive identification of such proteins has not yet been achieved
Ark floats gene therapy's boat, for now
sea-maid submitted, created time 3 weeks 5 days (www.nature.com)
In August, gene therapy's turbulent ride through the clinical rapids took a new twist as Ark Therapeutics released positive top-line results from a phase 3 trial of its adenoviral gene therapy Cerepro (sitimagene ceradenovec) for malignant brain tumors. Although the news boosted the London-based firm's shares, the course to market authorization and registration remains strewn with uncertainty—as Introgen, of Austin, Texas, found, to its cost, when the U.S
Statins Lower Blood Marker for Prostate Cancer
piggy submitted, created time 2 weeks 5 days (www.healthday.com)
THURSDAY, Oct. 30 (HealthDay News) -- A new study shows that men who take cholesterol-lowering drugs called statins have lower blood levels of prostate-specific antigen (PSA), a biomarker for prostate cancer risk.
That drop in PSA levels doesn't necessarily mean the drugs protect against disease, however, researchers say.
But it's possible that statins may offer some protection against the disease, said Dr. Robert Hamilton, one author of the report in the Oct. 28 issue of the Journal of the National Cancer Institute
Gene Variations Alter Risk of Esophageal Cancer
piggy submitted, created time 2 weeks 20 hours (www.sciencedaily.com)
ScienceDaily (Nov. 6, 2008) — Variations in a common gene pathway may affect esophageal cancer risk, a dangerous and rapidly increasing type of cancer, according to research by scientists at The University of Texas M. D. Anderson Cancer Center.
Results of the study, which is the first to look at the association between variations in genes related to microRNAs (miRNAs) and esophageal cancer, are published in the November issue of Cancer Prevention Research, a journal of the American Association of Cancer Research.
How Eating Red Meat Can Spur Cancer Progression: New Mechanism Identified
piggy submitted, created time 6 days 20 hours (www.sciencedaily.com)
Researchers at the University of California, San Diego School of Medicine, led by Ajit Varki, M.D., have shown a new mechanism for how human consumption of red meat and milk products could contribute to the increased risk of cancerous tumors.
Their findings, which suggest that inflammation resulting from a molecule introduced through consumption of these foods could promote tumor growth, are published online this week in advance of print publication in the Proceedings of the National Academy of Sciences (PNAS)
Tumor Secrets Written in Blood
piggy submitted, created time 2 days 20 hours (sciencenow.sciencemag.org)
Doctors may soon be able to use blood tests rather than invasive biopsies to figure out what type of brain tumors their patients have. The findings, which come thanks to new insights about how tumor cells communicate with their environment, may also bring physicians closer to the goal of more personalized medicine.
Cells are chatty, constantly exchanging proteins or electrical signals with their neighbors. For example, tumor cells can signal nearby blood vessels to grow in their direction, thereby facilitating tumor growth
A Sweet New Role for EGFR ...in Cancer!
jerry submitted, created time 6 months 1 week (www.cancercell.org)
The epidermal growth factor (EGFR) has served as an attractive bull's-eye for targeted cancer therapies.
Although the importance of EGFR as an oncogenic tyrosine kinase seems well established, this issue of Cancer Cell adds a new wrinkle to the role of EGFR in cancer. They find that this new function does not require EGFR kinase activity.
In this study, the authors demonstrate that EGFR facilitates glucose transport into cells by associating with and stabilizing a sodium/glucose cotransporter (SGLT1)
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Allatostatin I
Allatostatins (ASTs) of the Tyr/Phe-Xaa-Phe-Gly Leu/Ile-NH2 ...
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Moth Cytochrome C (MCC) (88-103)
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Peptide T
Peptide T is a chain of eight amino acids. It shares sequenc ...
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