250  Articles with the topic: Pharma & Medical Industry News
13

Ginkgo Biloba Does Not Reduce Dementia Risk, Study Shows

piggy submitted, created time 2 days 2 hours (www.sciencedaily.com)

The medicinal herb Ginkgo biloba does not reduce the risk of dementia or Alzheimer's disease development in either the healthy elderly or those with mild cognitive impairment, according to a large multicenter trial led by researchers at the University of Pittsburgh School of Medicine.

Findings from the Ginkgo Evaluation of Memory (GEM) Study, which is the first to have the necessary participant numbers and monitoring years to enable measurement of G. biloba's effectiveness and safety profile in dementia prevention, were just published in the Journal of the American Medical Association

11

Men who take aspirin have significantly lower PSA levels

sea-maid submitted, created time 3 days 22 hours (www.genengnews.com)

The use of aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) is significantly associated with lower PSA levels, especially among men with prostate cancer, say researchers at Vanderbilt University.

13

Should healthy people take statins too?

sea-maid submitted, created time 4 days 10 hours (www.nature.com)

The results of a study examining whether a potent cholesterol-lowering drug decreases the risk of heart disease are out. Rosuvastatin was given to 17,802 seemingly healthy people, and their chance of developing heart problems plummeted. The results, published in the New England Journal of Medicine, have revealed a number of questions about how to prevent heart attacks. Is exercise and a low-fat diet enough, or should large swathes of the population be prescribed preventative medication? Nature News gets to the heart of the matter.

10

Merck vaccine protects men from wart virus, too

sea-maid submitted, created time 1 week 1 day (www.reuters.com)

A vaccine designed to protect women and girls from cervical cancer caused by a wart virus may protect men, too, maker Merck and Co reported on Thursday

8

Bayer drug delays MS in half of patients-MRI study

sea-maid submitted, created time 1 week 2 days (www.alertnet.org)

A long-term study of brain scans in multiple sclerosis patients showed only about half of the patients who took the drug interferon beta 1-b got a long-lasting benefit, U.S. researchers said on Monday.

Patients in the small, three-year study were treated with the Bayer drug, which is sold under the trade name Betaseron in the United States or Betaferon elsewhere.

The drug is designed to reduce the number of disease flareups.

Multiple sclerosis occurs when the immune system attacks the myelin sheath protecting nerve cells. It affects 2

11

Industry shifts focus to immunology and cancer

sea-maid submitted, created time 1 week 3 days (www.nature.com)

Economic factors, including competition from generic drugs, is hitting even the big pharmaceutical companies hard, reports Nature. In 2010, Pfizer's Lipitor enters the public domain. For these reasons, the larger companies are narrowing the focus of their research, hitting fewer diseases. They're also working on fewer primary care drugs and more drugs that would be prescribed by specialists, such as cancer drugs.

"When Wyeth Pharmaceuticals announced last week that it would cut some of its research and development (R&D) programs in women's health, the decision seemed counterintuitive

11

Pfizer ends development of obesity drug

piggy submitted, created time 2 weeks 4 hours (www.reuters.com)

NEW YORK, Nov 5 (Reuters) - Pfizer Inc on Wednesday became the latest drugmaker to abandon an obesity treatment that works by blocking the receptors in the brain that makes people hungry after smoking marijuana.

The world's largest drugmaker said it was terminating late stage development of its experimental obesity drug, CP-945,598, citing a more conservative regulatory climate and problems seen with other medicines from the same class

12

GlaxoSmithKline's customized "red wine" drug potent in mice

piggy submitted, created time 2 weeks 22 hours (www.reuters.com)

LONDON (Reuters) - A drug in development that mimics a health-boosting compound found in red wine may be a powerful weapon in the fight against obesity and diabetes, researchers said on Tuesday.

A study of mice showed that the GlaxoSmithKline drug SRT1720 was about a thousand times more potent than resveratrol in activating an enzyme that helped the animals burn more energy and lower their insulin and glucose levels

11

HIV vaccine failure explained?

sea-maid submitted, created time 2 weeks 1 day (www.nature.com)

Researchers have suggested that an experimental vaccine against AIDS might have failed in part because it made some people's immune cells more vulnerable to HIV infection.

9

Genzyme and Osiris partner on stem-cell program

piggy submitted, created time 2 weeks 1 day (www.boston.com)

Genzyme Corp. and Osiris Therapeutics Inc. said today they will partner to develop and commercialize adult stem cell products with the potential to treat a variety of diseases.

In a press release describing the agreement, Genzyme of Cambridge said it will make a $130 million up-front payment to Maryland-based Osiris, with $75 million paid initially and $55 million to be paid on July 1, 2009. In addition, Osiris also has the potential to receive a total of up to $1.25 billion in milestone payments from Genzyme

10

Antibacterial drugs: New paths to beating bacteria

sea-maid submitted, created time 2 weeks 4 days (www.nature.com)

The need for new drugs to combat multidrug-resistant bacteria remains pressing. Now, two recent papers published in Science describe novel agents that target different mechanisms to currently approved antibacterials, which may help tackle this challenge.

The first study, by Haydon and colleagues, set out to target bacterial cell division. FtsZ is an essential bacterial protein that undergoes GTP-dependent polymerization to form the Z ring — the site of cell division — promoting the sequential recruitment of additional proteins that are vital to the process

8

Biogen, Genentech to codevelop cancer drug

piggy submitted, created time 2 weeks 5 days (finance.yahoo.com)

CAMBRIDGE, Mass. (AP) -- Biogen Idec Inc. said Thursday it will pay Genentech Inc. $31.5 million upfront under a deal to co-develop a potential cancer treatment.

The companies will develop GA101, now in early-to-midstage studies as a possible treatment for non-Hodgkins lymphoma and chronic lymphocytic leukemia. Both conditions are blood cancers.

9

Savient shares fall over gout drug safety concerns

sea-maid submitted, created time 3 weeks 3 days (biz.yahoo.com)

Shares of Savient Pharmaceuticals plunged Monday as Wall Street urged caution over the safety profile of the drug developer's candidate for gout treatment Puricase.

The stock plunged $8.51, or 73.5 percent, to $3.07. Earlier in the session, shares fell to $2.80, their lowest point in more than three years.

On Monday, Savient reported more late-stage study data on Puricase, reinforcing its effectiveness in prior results. If approved, the drug would be administered intravenously, with the goal of removing uric acid from the blood

9

VioQuest Pharmaceuticals Provides Strategic Alternatives Review, Announces Need for Capital and Possible Resignation of CEO, VP

sea-maid submitted, created time 3 weeks 3 days (www.fiercebiotech.com)

VioQuest Pharmaceuticalstoday provided a strategic alternatives review and operations update.

11

Pacgen Biopharmaceuticals Corporation Enters Into a Letter of Intent With Medigen Biotechnology Corporation

sea-maid submitted, created time 3 weeks 4 days (www.fiercebiotech.com)

Pacgen Biopharmaceuticals Corporation ("Pacgen" or the "Company") (TSX VENTURE: PGA) announced today that it has entered into a letter of intent for a business combination with Medigen Biotechnology Corp. ("Medigen"), a biotech company traded over the bulletin board in Taiwan. In connection with the transaction, Pacgen would acquire all of the issued and outstanding shares of Medigen by way of share purchase or through such other transaction structure as may be determined by the mutual agreement of Medigen and Pacgen

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