151 Articles with the topic: Psychiatry


Deep Brain Stimulation To Treat Psychiatric Diseases Reviewed
sea-maid submitted, created time 8 months 2 weeks (www.sciencedaily.com)
Pioneering therapeutic trials to investigate the effectiveness of deep brain stimulation (DBS) in hard-to-treat depression, obsessive-compulsive disorder (OCD) and Tourette's syndrome are underway at multiple medical centers around the world, according to a review in the June 2009 issue of Mayo Clinic Proceedings. 


Early Brain Marker for Familial Form of Depression: Structural Changes in Brain's Cortex
sea-maid submitted, created time 11 months 3 weeks (www.sciencedaily.com)
Findings from one of the largest-ever imaging studies of depression indicate that a structural difference in the brain – a thinning of the right hemisphere – appears to be linked to a higher risk for depression, according to new research at Columbia University Medical Center and the New York State Psychiatric Institute. 


Forget it! A biochemical pathway for blocking your worst fears?
piggy submitted, created time 11 months 3 weeks (www.eurekalert.org)
A receptor for glutamate, the most prominent neurotransmitter in the brain, plays a key role in the process of "unlearning," report researchers at the Salk Institute for Biological Studies. Their findings, published in the current issue of the Journal of Neuroscience, could eventually help scientists develop new drug therapies to treat a variety of disorders, including phobias and anxiety disorders, particularly post-traumatic stress disorder.
"Most studies focus on 'learning,' but the 'unlearning' process is probably just as important and much less understood," says Stephen F 


The Genetics of Fear: Study Suggests Specific Genetic Variations Contribute to Anxiety Disorders
piggy submitted, created time 1 year 1 week (www.psychologicalscience.org)
Polymorphisms are variations in genes which can result in changes in the way a particular gene functions and thus may be associated with susceptibility to common diseases. In a new study in Psychological Science, a journal of the Association for Psychological Science, psychologist Tina B. Lonsdorf and her colleagues from the Karolinska Institutet in Sweden and the University of Greifswald in Germany examined the effect of specific polymorphisms on how fear is learned and how that fear is subsequently overcome 


Brain Protein May Be Target for Fast-Acting Antidepressants
piggy submitted, created time 1 year 2 weeks (www.sciencedaily.com)
It takes weeks or months for most antidepressants to kick in, time that can feel like an eternity to those who need the drugs. But new research suggests that a protein called p11, previously shown to play a role in susceptibility to depression, activates a serotonin receptor in the brain known for producing a rapid antidepressant response. If scientists could develop drugs to target this receptor, then patients might feel the effects of their treatments in as little as two days.
In addition, the findings, reported by Rockefeller University’s Paul Greengard, Jennifer L 


Abuse Leaves Its Mark on the Brain
piggy submitted, created time 1 year 3 weeks (sciencenow.sciencemag.org)
Child abuse doesn't just cause emotional problems; it also causes long-lasting changes the brain. A new study shows that in men who were abused as children, a gene involved in stress control is affected even decades later, following a pattern also seen in stressed baby rats.
Rat studies have revealed that maternal neglect alters the workings of the hypothalamic-pituitary-adrenal (HPA) axis, a system that secretes particular hormones in response to stress 


Manic Depression News and Discussion Forum
nsujin submitted, created time 1 year 1 month (www.manicdepression.us.com)
Find the latest news about depression, bipolar disorder and schizophrenia. Discuss mood disorder topics with members of the health community. 


Psychoactive compound activates mysterious receptor
piggy submitted, created time 1 year 1 month (www.eurekalert.org)
A hallucinogenic compound found in a plant indigenous to South America and used in shamanic rituals regulates a mysterious protein that is abundant throughout the body, University of Wisconsin-Madison researchers have discovered.
The finding, reported in the Feb. 13 issue of Science, may ultimately have implications for treating drug abuse and/or depression. Many more experiments will be needed, the researchers say.
Scientists have been searching for years for naturally occurring compounds that trigger activity in the protein, the sigma-1 receptor 


Older antidepressants work for Parkinson patients
piggy submitted, created time 1 year 3 months (www.reuters.com)
People with Parkinson's disease who also suffer from depression may find they're helped more by an older class of antidepressants than newer types of medication, a small clinical trial sponsored by the National Institutes of Health suggests.
The study found that paroxetine (brand name, Paxil), a so-called SSRI antidepressant, appears to be less effective than the "tricyclic" antidepressant nortriptyline for treating depression in patients with Parkinson's disease.
"Depression in Parkinson's disease is underrecognized, underappreciated and undertreated," lead investigator Dr 


DSM-IV gets reexamined. Expect a DSM-V in a few years.
Darkfrog submitted, created time 1 year 3 months (www.nytimes.com)
Psychologists are revising the DSM-IV. The Diagnostic and Statistical Manual of Mental Disorders has been altered a few times since its first edition came out in 1952 (hence the "IV") to reflect better information and changing ideas about what makes a healthy mind. For example, earlier versions of the DSM listed homosexuality as a disease. The DSM-IV does not 


Antidepressant treatment may reduce male fertility
piggy submitted, created time 1 year 4 months (www.reuters.com)
Treatment with paroxetine (Paxil), which belongs to the selective serotonin reuptake inhibitor (SSRI) class of antidepressant drugs, increases DNA fragmentation in sperm, according to research presented today at the sixty-fourth annual meeting of the American Society for Reproductive Medicine in San Francisco.
Although the study did not directly evaluate male fertility, the fivefold increase in the number of men who developed abnormal sperm DNA while being treated with paroxetine is "troubling" and "suggests an adverse effect on fertility," co-investigator Dr 


Depression and the Nobel Prize
sea-maid submitted, created time 1 year 4 months (well.blogs.nytimes.com)
Anyone who has struggled with depression—either in themselves or a loved one—will be moved by the story of Douglas C. Prasher.
Dr. Prasher, who now drives a courtesy van for a car dealer, abandoned a life of scientific research years ago. Trained as a biochemist, Dr. Prasher has struggled over the years with bouts of depression.
His story wouldn’t be notable except for a startling fact: his early research led to a Nobel Prize-winning discovery about the inner workings of living cells. Dr 


sea-maid submitted, created time 1 year 5 months (www.nature.com)
Since the time of ancient Egypt, societies have struggled to understand mental illness and to care for those affected by it. But, over the millennia, the idea that mental illness might have a biological cause arose only intermittently, and treatments ranged from the benign (exercise, humour and music) to the barbaric (exorcism, imprisonment and lobotomy). By the mid-twentieth century, however, several breakthroughs had been made 


NIH Suspends Grant to Emory University
jerry submitted, created time 1 year 5 months (sciencenow.sciencemag.org)
The National Institutes of Health (NIH) has suspended a $9 million grant for a depression study led by psychiatrist Charles Nemeroff at Emory University in Atlanta. The punishment, imposed in August but only made public today, is apparently the most severe reaction by NIH so far to a Senate investigation of NIH-funded researchers who may have failed to report all of their income from drug companies.
Recipients of NIH grants are required to report income from industry consulting activities 


UPDATE 1-FDA Backs Astra's Seroquel XR for bipolar disorder
jerry submitted, created time 1 year 5 months (www.reuters.com)
U.S. regulators have approved AstraZeneca's (AZN.L: Quote, Profile, Research, Stock Buzz) drug Seroquel XR as a treatment for bipolar disorder, extending the medicine's use beyond schizophrenia, the Anglo-Swedish company said ... 