33 Articles with the topic: Respiratory Disorders
Cell: A key pathway of acute lung injury-Oxidative
kavin submitted, created time 6 months 4 weeks (www.cell.com)
Multiple lung pathogens such as SARS cause high lethality due to acute respiratory distress syndrome. The researchers, through experiments in mice, indentify oxidative stress and innate immunity as key lung injury pathways that control the severity of ALI. 
Hair of the dog keeps children’s allergies at bay
kavin submitted, created time 6 months 3 weeks (www.msnbc.msn.com)
Recently, many researchers have suggested that having a dog in the house reduces the risk that young children will develop allergies. They believe youngsters may get beneficial early exposure to germs carried into the house on the animal’s fur, which helps their immune systems develop.
Drug taken to stop smoking is linked to traffic mishaps
sea-maid submitted, created time 5 months 3 weeks (www.latimes.com)
A surprising development: the drug that the man in this study had hoped would help turn him into a healthier person instead, he believes, caused an accident in which he could have been seriously hurt, even killed.
Faulty DNA repair could be a risk factor for lung cancer in nonsmokers
sea-maid submitted, created time 4 months 3 weeks (esciencenews.com)
People who have never smoked but whose cells cannot efficiently repair environmental insults to DNA are at higher risk of developing lung cancer than those with effective genomic repair capability, according to researchers from the Department of Epidemiology at The University of Texas M. D. Anderson Cancer Center. "About 15 percent of lung cancers occur in lifetime never smokers
Female physicians most effective at treating childhood asthma
kavin submitted, created time 3 months 4 days (www.biomedcentral.com)
Female physicians have a better perception of asthma symptoms in children than their male counterparts, according to Turkish researchers.
The finding could indicate significant contribution of gender-related factors in clinical attitudes and beliefs,Bulent Sekerel (Hacettepe University Faculty of Medicine, Ankara, Turkey) and colleagues explain in the journal BMC Health Services Research.
Understanding the level of management ability of physicians may guide interventions to improve quality of care and patient outcomes,?the authors write
Tissue engineering triumph: Doctors transplant a trachea made from the patient's own stem cells
Darkfrog submitted, created time 1 day 21 hours (www.lancet.com)
The medical journal Lancet has just announced that doctors have performed the first successful trachea transplant using a trachea crafted from the patient's own stem cells. The New York Times is hailing this as a revolutionary step in regenerative medicine. The surgery took place in Barcelona this past June. Researchers from universities in Spain, Britain and Italy collaborated on the preparation. The patient's original trachea--actually one of her bronchi--had been damaged by severe tuberculosis.
Prof
Experimental chemotherapy regimen shows promise in treating advanced lung cancer
sea-maid submitted, created time 3 months 1 week (www.eurekalert.org)
A combination of chemotherapy agents that have been tested in other tumor types appears to be a promising alternative to standard treatment for advanced nonsmall cell lung cancer, according to a report in the Aug. 15 issue of Clinical Cancer Research, a journal of the American Association for Cancer Research.
Scientists Develop Breathalyzer for Disease
Sue Wu submitted, created time 9 months 1 day (www.efluxmedia.com)
It may one day be possible to walk into your doctor's office and breathe into a small device that will tell you if you are in the earliest stage of a wide range of diseases from lung cancer to asthma to kidney failure.
Bosentan benefits in mild pulmonary arterial hypertension
kavin submitted, created time 4 months 3 weeks (www.thelancet.com)
The EARLY study, published in the June 21, 2008 issue of the Lancet, was conducted by a group led by Dr Nazzareno Galiè (University of Bologna, Italy).
They note that bosentan has been shown to improve exercise capacity, hemodynamics, and delay clinical worsening in two pivotal clinical trials, but in these, like other trials of treatments for pulmonary arterial hypertension, the vast majority of enrolled patients were in an advanced symptomatic state (WHO functional class 3 and 4)
Burning incense linked to respiratory cancers
sea-maid submitted, created time 2 months 3 weeks (www.reuters.com)
Burning incense may create a sweet scent, but regularly inhaling the smoke could put people at risk of cancers of the respiratory tract, researchers reported Monday.
Terriers Join Fight Against a Killer Disease in Humans
Eric wu submitted, created time 10 months 3 weeks (www.livescience.com)
The West Highland White Terrier, called "Westies," gets a disease very similar to humans' idiopathic pulmonary fibrosis, which kills as many people as breast cancer. In humans and in dogs, the patient's lungs slowly turn to scar tissue.
However, pedigree dogs' breeding records are very well kept and their disease progresses faster, making them a good model for the disease. Although, understandably, not many dog owners are volunteering their sick dogs for animal testing, it is hard to get them to agree even to donate their dogs' bodies after they die.
Epigenetic Regulation of EpCAM in Tumor Invasion and Metastasis
MedUnion submitted, created time 9 months 1 week (www.mupnet.com)
Metastatic progression is the cause of most cancer decease. Many cell surface adhesion molecules are known to be present or re-expressed following gene promoter CpG island hypomethylation in the early stage of growing tumors, but absent or reduced by gene promoter CpG hypermethylation in metastasized carcinomas. Recent studies have revealed that an adhesion receptor, epithelial cell adhesion molecule (EpCAM), mediates cell-cell interaction and is involved in tumor invasion and metastasis. EpCAM expression was associated with promoter CpG methylation in lung adenocarcinoma
Expression and Prognostic Significance of EpCAM
MedUnion submitted, created time 9 months 1 week (www.mupnet.com)
AIM: EpCAM (CD326) is a transmembrane glycoprotein on epithelial cells. To assess its expression, an increasing number of commercially available antibodies combined with multiple staining protocols with varying sensitivities and specificities are in use. There is no consensus about definition of positivity. Systematic and reliable comparison of results is therefore hampered. To maximise the reproducibility of the results, we investigated EpCAM expression on tissue microarrays
Quitting smoking is a pack behavior
sea-maid submitted, created time 5 months 4 weeks (blog.seattlepi.nwsource.com)
Smokers tend to quit in groups, according to a new study. One person who quits can have ripple effects across his or her entire social network, prompting others to kick the habit.
Obesity and asthma: Possible mechanisms
jerry submitted, created time 5 months 3 weeks (www.jacionline.org)
Obesity and asthma may share a common etiology, such as common genetics, common in utero conditions, or common predisposing dietary factors. Novel therapeutic strategies for treatment of the obese patient with asthma may result from an increased understanding of the mechanisms underlying this relationship
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